Dry skin in the winter is related to the ceramide profile in the stratum corneum and can be improved by treatment with a <i><scp>E</scp>ucalyptus</i> extract

Ishikawa, Junko; Yoshida, Hiroshi; Ito, Shotaro; Naoe, Ayano; Fujimura, Tsutomu; Kitahara, Takashi; Zerweck, Charles; Grove, Gary L.

doi:10.1111/jocd.12019

Cited by 33 publications

(40 citation statements)

References 24 publications

(31 reference statements)

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“…It is reported that the ceramide composition, which is catalyzed by several enzymes, strongly correlates with dry skin conditions and skin conductance. 23 Other molecules involved in the maturation of keratinocytes can be candidates that are influenced by blood flow. To clarify the mechanisms underlying skin physiology affected by blood flow functionality, further in vivo and/or in vitro analysis is required.…”

Section: Discussionmentioning

confidence: 99%

Dry skin conditions are related to the recovery rate of skin temperature after cold stress rather than to blood flow

et al. 2016

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Section: Discussionmentioning

confidence: 99%

Dry skin conditions are related to the recovery rate of skin temperature after cold stress rather than to blood flow

et al. 2016

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“…O teor de água do estrato córneo e lipídios de superfície como ceramidas e colesterol formam um equilíbrio, o que é muito importante para a função e aparência da pele. As bicamadas lipídicas e a água formam uma estrutura de gel cristalino líquido multilamelarintercelular que está envolvida na prevenção da perda de água transepidermal (14) . A barreira normal da pele é o principal aspecto da homeostase e regeneração da pele.…”

Section: Discussionunclassified

“…The water content of the stratum corneum and surface lipids such as ceramides and cholesterol form a balance, which is very important for the function and appearance of the skin. Lipid bilayers and water form an intercellular multilamellar liquid crystalline gel structure that is involved in preventing transepidermal water loss (14) . A normal skin barrier is the main aspect of skin homeostasis and regeneration.…”

Section: Discussionmentioning

confidence: 99%

Immediate and long term effects of a cosmetic formulation with Cichorium intybus root extract

Paseto¹,

Wagemaker²,

Campos³

2017

BBR

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220 Biomedical and Biopharmaceutical Research J o r n a l d e I n v e s t i g a ç ã o B i o m é d i c a e B i o f a r m a c ê u t i c a Immediate and long term effects of a cosmetic formulation with Cichorium intybus root extract AbstractDry skin is characterized as a rough and scaling skin surface. It usually has lower water content than normal skin. Vitamin D helps to regulate cellular proliferation and differentiation andcan help to protect skin from environmental factors. However, the stability vitamin D in cosmetic formulations is low. Thus, the aim of this study was to evaluate the sensory properties and protective effects on skin hydration of a cosmetic formulation containing Cichorium intybus root extract, previously shown to be "vitamin D like" (VD). A formulation containing VD or not (vehicle) was applied on the arm, forearm and face of fifteen subjects. Measurements of stratum corneum water content, Transepidermal Water Loss (TEWL) and skin microrelief parameters were performed using biophysical and skin image techniques before (baseline), after 2 hours, and after 45 and 90 days of daily application of the formulations. Only the formulation with VD was effective in maintaining skin barrier function and skin hydration under low humidity conditions. Cichorium intybus root extract is shown to be an effective "vitamin D like" active ingredient to use in cosmetic formulations to avoid skin dryness. In addition, the extract maintained the sensory properties of the studied cosmetic formulation.Keywords: Cichorium intybus root extract, "Vitamin D-like", cosmetics, biophysical techniques, skin dryness, sensory properties ResumoA pele seca é caracterizada como uma superfície áspera, com menor teor de água do que a pele normal. A Vitamina D ajuda a regular a proliferação e diferenciação celular e pode ajudar a proteger a pele contra fatores ambientais. No entanto, a Vitamina D é instável em formulações cosméticas. Assim, o objetivo deste estudo foi avaliar o sensorial e os efeitos protetores na hidratação da pele de uma formulação cosmética contendo extracto de raiz Cichorium intybus -"Vitamina D like" (VD). A formulação, adicionada ou não (veículo) de VD, foi aplicada no braço, antebraço e na face de quinze participantes. Antes (basal) e após 2 horas, 45 e 90 dias de aplicação diária das formulações foram realizadas medidas do conteúdo aquoso do estrato córneo, perda de água transepidémica e parâmetros do microrrelevo da pele por técnicas biofísicas e análise de imagem. Apenas a formulação com VD foi efetiva na manutenção da função barreira e hidratação da pele em condições de baixa umidade. Assim, oextracto de raíz de Cichorium intybus é um ingrediente ativo eficaz para aplicação em cosméticos para evitar o ressecamento da pele. Além disso, a "Vitamina D like" melhorou o sensorial da formulação cosmética estudada.Palavras chave: extracto de raiz de Cichorium intybus, "Vitamina D-like", cosméticos, técnicas de biofísica, pele seca, propriedades sensoriais.

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“…Ceramides can combine with water and prevent water decrease in the SC because ceramides have hydrophilic lipid. In recent years, ceramides have been developed for cosmetics, which are responsible for the permeability barrier and water holding functions of the epidermis [7,8].…”

Section: Introductionmentioning

confidence: 99%

Biosynthesis of myristyl serinate by immobilized Candida antarctica lipase in two-phase system

Cai

et al. 2014

Journal of Molecular Catalysis B: Enzymatic

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Dry skin in the winter is related to the ceramide profile in the stratum corneum and can be improved by treatment with a Eucalyptus extract

Abstract: These results suggest that not only the level of CER, but also specific CER species strongly contribute to dry skin relief and products that increase those are useful to improve dry skin conditions.

Cited by 33 publications

References 24 publications

Dry skin conditions are related to the recovery rate of skin temperature after cold stress rather than to blood flow

Dry skin conditions are related to the recovery rate of skin temperature after cold stress rather than to blood flow

Immediate and long term effects of a cosmetic formulation with Cichorium intybus root extract

Biosynthesis of myristyl serinate by immobilized Candida antarctica lipase in two-phase system

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