Drug therapy of Alzheimer's disease: Realistic or not?

The Families of Cognition Enhancers

“…The ring-extended analogues of piracetam are shown in Fig. Ib: teDilsetam (CAS-997;Saletu et aI., 1989;Semlitsch et a1., 1989;Anonymous, 1988a;Saletu et aI., 1987a and1986a;Wesneset aI., 1987) is eurrently in phase 11 clinical investigation, whereas alaptide (VUFB-15 754;Krejci et aI., 1986) is undergoing phase I clinical trials. The last two compounds are at the stage of pharmacological evaluation.…”

The Families of Cognition Enhancers

“…The ring-extended analogues of piracetam are shown in Fig. Ib: teDilsetam (CAS-997;Saletu et aI., 1989;Semlitsch et a1., 1989;Anonymous, 1988a;Saletu et aI., 1987a and1986a;Wesneset aI., 1987) is eurrently in phase 11 clinical investigation, whereas alaptide (VUFB-15 754;Krejci et aI., 1986) is undergoing phase I clinical trials. The last two compounds are at the stage of pharmacological evaluation.…”

Psychostimulants, Analeptics, Nootropics: An Attempt to Differentiate and Assess Drugs Designed for the Treatment of Impaired Brain Functions

“…Nootropics, psychostimulants, and analeptics are three classes of drugs that stimulate the CNS and which are, or have been, used with varying success in the treatment of impaired brain functions (Hollister, 1986). Oespite their use in similar situations, these drugs exhibit completely different profiles of action, and there is still disagreement in the literature about where to draw the line between the classes and about the criteria for therapeutic application.…”

The Families of Cognition Enhancers

“…The ring-extended analogues of piracetam are shown in Fig. Ib: teDilsetam (CAS-997;Saletu et aI., 1989;Semlitsch et a1., 1989;Anonymous, 1988a;Saletu et aI., 1987a and1986a;Wesneset aI., 1987) is eurrently in phase 11 clinical investigation, whereas alaptide (VUFB-15 754;Krejci et aI., 1986) is undergoing phase I clinical trials. The last two compounds are at the stage of pharmacological evaluation.…”

Psychostimulants, Analeptics, Nootropics: An Attempt to Differentiate and Assess Drugs Designed for the Treatment of Impaired Brain Functions

“…Nootropics, psychostimulants, and analeptics are three classes of drugs that stimulate the CNS and which are, or have been, used with varying success in the treatment of impaired brain functions (Hollister, 1986). Oespite their use in similar situations, these drugs exhibit completely different profiles of action, and there is still disagreement in the literature about where to draw the line between the classes and about the criteria for therapeutic application.…”

The Families of Cognition Enhancers

“…The ring-extended analogues of piracetam are shown in Fig. Ib: teDilsetam (CAS-997;Saletu et aI., 1989;Semlitsch et a1., 1989;Anonymous, 1988a;Saletu et aI., 1987a and1986a;Wesneset aI., 1987) is eurrently in phase 11 clinical investigation, whereas alaptide (VUFB-15 754;Krejci et aI., 1986) is undergoing phase I clinical trials. The last two compounds are at the stage of pharmacological evaluation.…”

Psychostimulants, Analeptics, Nootropics: An Attempt to Differentiate and Assess Drugs Designed for the Treatment of Impaired Brain Functions

“…Nootropics, psychostimulants, and analeptics are three classes of drugs that stimulate the CNS and which are, or have been, used with varying success in the treatment of impaired brain functions (Hollister, 1986). Oespite their use in similar situations, these drugs exhibit completely different profiles of action, and there is still disagreement in the literature about where to draw the line between the classes and about the criteria for therapeutic application.…”