Drug resistance analysis of bacterial strains isolated from burn patients

Abstract

ABSTRACT.This study aimed to analyze the spectrum and drug resistance of bacteria isolated from burn patients to provide a reference for rational clinical use of antibiotics. Up to 1914 bacterial strain specimens isolated from burn patients admitted to hospital between 2001 and 2010 were subjected to resistance monitoring by using the K-B paper disk method. Retrospective analysis was performed on drug resistance analysis of burn patients. 9727-9734 (2014) resistance, respectively. Antibacterial drugs that had drug resistance rates to MRSE and MRSA higher than 90% accounted for 38.9 and 72.2%, respectively, whereas those with lower than 30% drug resistance rates accounted for 11.1 and 16.7%, respectively. The burn patients enrolled in the study were mainly infected with G -bacteria. These results strongly suggest that clinicians should practice rational use of antibiotics based on drug susceptibility test results.

Bacteriological Profile and Antibacterial Sensitivity Patterns of Isolates among Burn Patients in Sulaimani City

“…A study by Behzadnia, S., et al is agree with this result [6]. But a study by Wang, L.F., and his coauthors found that A. baumannii is the most common bacterial cause infection in burn patients [23]. The factor which may be lead to the presence of much Acinetobacter on a normal skin commensal and upper respiratory airway and it spreads easily [24].…”

“…A previous study by Wang, L.F., and his coauthors demonstrated that the drug resistant to A. baumannii due to easily produce drug resistance by combining plasmid. A variety of resistant plasmids coexist, such as plasmid-mediated TEM-1 and TEM-2, TEM-2 β-lactamase, and chromosome-mediated β-lactamase; the change in penicillin-binding proteins and the permeability decrease of outer membrane proteins and also result drug resistance [23].…”

Evaluation of genipin-crosslinked chitosan hydrogels as a potential carrier for silver sulfadiazine nanocrystals

“…It has been proved that skin wounds are susceptible to infections caused by gram-positive bacteria like Staphylococcus aureus, and gram-negative bacteria like Escherichia coli, Pseudomonas aeruginosa [1]. Infection of wound surfaces often causes delayed healing or nonhealing of the wound, which results in mortality [2].…”

First report of coexistence of AmpC beta-lactamase genes in Klebsiella pneumoniae strains isolated from burn patients

“…Unfortunately, during recent decades the widespread use of antibiotics led to the emergence of drug-resistant bacteria, such as multidrug and extensively drugresistant organisms. Thus in that area, precise knowledge of the bacterial resistance patterns is essential for determining the best antibiotic regimens or empirical therapy in critical conditions, for treatment of burn patients [1].…”