Drug-induced “Allergic hepatitis”

Podevin, Philippe; Biour, M

doi:10.1007/bf02771763

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Cited by 9 publications

References 97 publications

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Allergic Reactions to Drugs and Biologic Agents

deShazo¹

1997

JAMA

181

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Drug allergies are adverse reactions resulting from immunologic responses to drugs or their metabolites. These reactions result in predictable patterns of organ-specific or systemic hypersensitivity that usually recur on subsequent exposure to the same drug. Although diagnostic testing for drug allergy is available for only a few drugs, protocols have been developed to assist in management of allergic reactions to many drugs and biologic agents. Other protocols assist in the management of patients who develop drug reactions while undergoing multiple drug therapy or those with a history of adverse drug reactions who again require treatment for the same condition.

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Allergic Reactions to Drugs and Biologic Agents

deShazo¹

1997

JAMA

181

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Mitochondrial and immunoallergic injury increase risk of positive drug rechallenge after drug-induced liver injury: A systematic review

Hunt

2010

Hepatology

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Drug rechallenge following drug‐induced liver injury

et al. 2017

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For critical medicines, drug rechallenge may be appropriate when 1) no safer alternatives are available, 2) the objective benefit exceeds the risk, and 3) patients are fully informed and consent, can adhere to follow-up, and alert providers to hepatitis symptoms. To better understand rechallenge outcomes and identify key risk factors for positive rechallenge, additional data are needed from controlled clinical trials, prospective registries, and large health care databases. (Hepatology 2017;66:646-654).

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Drug-induced “Allergic hepatitis”

Cited by 9 publications

References 97 publications

Allergic Reactions to Drugs and Biologic Agents

Allergic Reactions to Drugs and Biologic Agents

Mitochondrial and immunoallergic injury increase risk of positive drug rechallenge after drug-induced liver injury: A systematic review

Drug rechallenge following drug‐induced liver injury

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