Abstract:With the development of solid-phase
synthesis and DNA nanotechnology,
DNA-based drug delivery systems have seen large advancements over
the past decades. By combining various drugs (small-molecular drugs,
oligonucleotides, peptides, and proteins) with DNA technology, drug-grafted
DNA has demonstrated great potential as a promising platform in recent
years, in which complementary properties of both components have been
discovered; for instance, the synthesis of amphiphilic drug-grafted
DNA has enabled the produ… Show more
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