Giorgos Tsoumpekos, Linda Nemetschke, Elisabeth Knust
Abstract:How signaling and scaffolding proteins are coordinated apically to control junctional tension and hence epithelial cell growth is unclear. Tsoumpekos et al. identify the Drosophila scaffolding protein Big bang as a novel regulator of growth in epithelial cells of the wing disc by showing that big bang ensures proper junctional tension and apical cytocortex organization.
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