Droplet transportation by adjusting the temporal phase shift of surface acoustic waves in the exciter–exciter mode

Sui, Mingyang; Dong, Huijuan; Mu, Guanyu; Xia, Jingze; Zhao, Jie; Yang, Zhen; Li, tianlong; Sun, Tong; Grattan, K.T.V.

doi:10.1039/d2lc00402j

Cited by 8 publications

(4 citation statements)

References 59 publications

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“…Simultaneously, the interior acoustic pressure also actuates the droplet to move forward (i.e., where the wavelengths of the TSAWs are much smaller than the size of the droplet). 24,27,28,37 After initial actuation, the excitation signal frequency may be further fine-tuned to shift the propagation paths of the TSAWs for centrifugation to enhance the agglomeration of particles if needed. 38 The simulations in Fig.…”

Section: Working Principlementioning

confidence: 99%

Acoustofluidics for simultaneous droplet transport and centrifugation facilitating ultrasensitive biomarker detection

Qian,

Lan,

Huang

et al. 2023

Lab Chip

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Section: Working Principlementioning

confidence: 99%

Acoustofluidics for simultaneous droplet transport and centrifugation facilitating ultrasensitive biomarker detection

Qian,

Lan,

Huang

et al. 2023

Lab Chip

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Section: Acoustic Manipulation Techniques Commonly Used In Biological...mentioning

confidence: 99%

“…The “excitation-absorption” mode can also be used to generate travelling surface acoustic waves (TSAW), so that liquid-based transportation of micro/nano robots can be achieved. TSAW could be formed either by the use of sound-absorbing gels ( Renaudin et al, 2006 ; Li et al, 2007 ; Collignon et al, 2015 ) or by setting a spatial phase difference between the pairs of the IDTs ( Sui et al, 2022 ; Dong et al, 2023 ), as shown in Figure 2B . Another method for forming TSAW is to use single curved-shape transducer that operates at high excitation frequency from 100 MHz to 1 GHz ( Destgeer et al, 2017 ).…”

Section: Acoustic Manipulation Techniques Commonly Used In Biological...mentioning

confidence: 99%

Acoustic-propelled micro/nanomotors and nanoparticles for biomedical research, diagnosis, and therapeutic applications

Mu,

Qiao,

Sui

et al. 2023

Front. Bioeng. Biotechnol.

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Acoustic manipulation techniques have gained significant attention across various fields, particularly in medical diagnosis and biochemical research, due to their biocompatibility and non-contact operation. In this article, we review the broad range of biomedical applications of micro/nano-motors that use acoustic manipulation methods, with a specific focus on cell manipulation, targeted drug release for cancer treatment and genetic disease diagnosis. These applications are facilitated by acoustic-propelled micro/nano-motors and nanoparticles which are manipulated by acoustic tweezers. Acoustic systems enable high precision positioning and can be effectively combined with magnetic manipulation techniques. Furthermore, acoustic propulsion facilitates faster transportation speeds, making it suitable for tasks in blood flow, allowing for precise positioning and in-body manipulation of cells, microprobes, and drugs. By summarizing and understanding these acoustic manipulation methods, this review aims to provide a summary and discussion of the acoustic manipulation methods for biomedical research, diagnostic, and therapeutic applications.

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“…In addition to their frequent use in particles and cell manipulation, SAWs are also commonly utilized for driving the trapping [ 33 ] and splitting [ 34 ] of liquid droplets in channels as well as for the manipulation [ 35 ] of sessile droplets, which includes techniques such as translation [ 36 ], combination [ 37 ], pumping [ 38 , 39 ], mixing [ 40 , 41 ], merging [ 42 ], atomization [ 43 , 44 , 45 , 46 ], and jetting [ 12 , 47 ].…”

Section: Introductionmentioning

confidence: 99%

A Comprehensive Review of Surface Acoustic Wave-Enabled Acoustic Droplet Ejection Technology and Its Applications

Ning,

Lei,

et al. 2023

Micromachines

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This review focuses on the development of surface acoustic wave-enabled acoustic drop ejection (SAW-ADE) technology, which utilizes surface acoustic waves to eject droplets from liquids without touching the sample. The technology offers advantages such as high throughput, high precision, non-contact, and integration with automated systems while saving samples and reagents. The article first provides an overview of the SAW-ADE technology, including its basic theory, simulation verification, and comparison with other types of acoustic drop ejection technology. The influencing factors of SAW-ADE technology are classified into four categories: fluid properties, device configuration, presence of channels or chambers, and driving signals. The influencing factors discussed in detail from various aspects, such as the volume, viscosity, and surface tension of the liquid; the type of substrate material, interdigital transducers, and the driving waveform; sessile droplets and fluid in channels/chambers; and the power, frequency, and modulation of the input signal. The ejection performance of droplets is influenced by various factors, and their optimization can be achieved by taking into account all of the above factors and designing appropriate configurations. Additionally, the article briefly introduces the application scenarios of SAW-ADE technology in bioprinters and chemical analyses and provides prospects for future development. The article contributes to the field of microfluidics and lab-on-a-chip technology and may help researchers to design and optimize SAW-ADE systems for specific applications.

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Droplet transportation by adjusting the temporal phase shift of surface acoustic waves in the exciter–exciter mode

Abstract: Droplet actuation using Surface Acoustic Wave (SAW) technology has been widely employed in ‘lab-on-a-chip’ applications, such as for on-chip Polymerase Chain Reactions. The current strategy uses the Exciter-Absorber mode (exciting...

Cited by 8 publications

References 59 publications

Acoustofluidics for simultaneous droplet transport and centrifugation facilitating ultrasensitive biomarker detection

Acoustofluidics for simultaneous droplet transport and centrifugation facilitating ultrasensitive biomarker detection

Acoustic-propelled micro/nanomotors and nanoparticles for biomedical research, diagnosis, and therapeutic applications

A Comprehensive Review of Surface Acoustic Wave-Enabled Acoustic Droplet Ejection Technology and Its Applications

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