Dramatic Effect of Levetiracetam on Posthypoxic Myoclonus: Difficult Weaning From Mechanical Ventilation

Muslu, Bünyamin; Kilci, Oya; Horasanlı, Eyüp; Dikmen, Bayazıt

doi:10.1097/01.wnf.0000265978.72772.2d

Cited by 4 publications

(2 citation statements)

References 15 publications

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“…8 Basic therapeutic regimens of PHM are empirical and include different combinations of piracetam, valproate, levetiracetam, and clonazepam. 9 Lacosamide, sodium oxybate, and 5-hydroxytryptophane are useful in some cases. 10,11 In the present case, the patient experienced dramatic improvement in her myoclonus after switching her antidepressant treatment.…”

Section: Discussionmentioning

confidence: 99%

Relief of Intractable Posthypoxic Myoclonus After Administration of Agomelatine

Aleja

Saiz-Díaz

Peña

2012

Clinical Neuropharmacology

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Chronic posthypoxic myoclonus is characterized by myoclonic jerks that are specifically triggered by action. It is a rare but devastating sequela of hypoxic encephalopathy. We report a 42-year-old female patient with treatment-resistant chronic posthypoxic myoclonus, which improved with administration of the drug agomelatine. We suggest that agomelatine could represent a useful therapeutic option in the treatment of chronic posthypoxic myoclonus.

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Section: Discussionmentioning

confidence: 99%

Relief of Intractable Posthypoxic Myoclonus After Administration of Agomelatine

Aleja

Saiz-Díaz

Peña

2012

Clinical Neuropharmacology

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“…Katılımcıların küçük bir bölümünün levetirastamı MAE'de tekli tedavide kullanabileceğini bildirmesinin hekim deneyiminin ilaç tercihindeki etkisini gösterdiğini düşünüyoruz. Çünkü, levetirasetamın diğer myoklonik epileptik sendromlar ve hipoksik beyin hasarı sonrasındaki myoklonilere etkili olduğu son zamanlarda vakalar ile tartışılmaya başlanmıştır (13,14) . Absans epilepside valproik asit, etosuksimid ve lamotrijinin etkinliğinin benzer olduğu bildirilmiştir (15) .…”

Section: Discussionunclassified