2008
DOI: 10.1007/978-1-59745-379-0_12
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Abstract: Down-regulation of endogenous genes via post-transcriptional gene silencing (PTGS) is a key to the characterization of gene function in plants. Many RNA-based silencing mechanisms such as post-transcriptional gene silencing, co-suppression, quelling, and RNA interference (RNAi) have been discovered among species of different kingdoms (plants, fungi, and animals). One of the most interesting discover ies was RNAi, a sequence-specific gene-silencing mechanism initiated by the introduction of double-stranded RNA …

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