Dowling-Degos disease associated with hidradenitis suppurativa

Bedlow, A. J.; Mortimer, Peter

doi:10.1111/j.1365-2230.1996.tb00103.x

Cited by 45 publications

(30 citation statements)

References 7 publications

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“…It is difficult to say if this is a significant association, as usually people do not seek medical advice for these pigment changes, which are discovered during examination of the groin and armpits of HS patients [21].…”

Section: Dowling-degos-kitamura Diseasesmentioning

confidence: 99%

Hidradenitis suppurativa

Revuz

2010

La Presse Médicale

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Hidradenitis suppurativa, or Verneuil's disease, is somewhat common, especially in women, but it often unrecognized. Clinical manifestations include painful nodules, abscesses, sinus tracts, and ropelike hypertrophic scars in the apocrine gland-bearing areas. It is a chronic disease. Smoking and overweight are risk factors, but the cause is unknown: it is a disease of the follicular apparatus, neither infectious nor hormonal. Severe dramatic forms are rare. Quality of life is severely affected even in the mild forms. Treatment is both medical and surgical: wide-spectrum antibiotics and excisions tailored to the extent of involvement. Anti-TNFα drugs are effective, but their risk-benefit ratio is still in question. Laser treatment is under study.

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Section: Dowling-degos-kitamura Diseasesmentioning

confidence: 99%

Hidradenitis suppurativa

Revuz

2010

La Presse Médicale

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“…Often Dowling-Degos disease is associated with chronic hidradenitis suppurativa. It is speculated that abnormal epithelial proliferation involves mainly the pilosebaceous unit and this follicular occlusion may indicate a predisposition for the development of hidradenitis suppurativa [46, 47]. In reticulate acropigmentation of Kitamura, atrophic pigmented freckle-like macules occur symmetrically on the dorsum of the hands and feet and the palms may show pits [42, 45].…”

Section: Reticulate Flexural Pigmentary Disorders (Mim 179850) and Lmentioning

confidence: 99%

Genodermatosis with Reticulate, Patchy and Mottled Pigmentation of the Neck – A Clue to Rare Dermatologic Disorders

Itin

Lautenschläger

1998

Dermatology

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Reticulate pigmentation of the neck is a common finding in numerous genodermatoses and acquired diseases. As the neck is readily accessible to medical inspection, it may serve as a diagnostic window for various dermatoses. Several entities out of the spectrum of ectodermal dysplasia present with reticulate or mottled pigmentation on the upper trunk and neck. The most impressive genodermatoses with punctate and reticulate pigmentation affecting the neck are the Naegeli-Franceschetti-Jadassohn syndrome, dermatopathia pigmentosa reticularis and dyskeratosis congenita. Reticulate pigmented anomaly of the flexures and lentiginosis, disorders of cornification and related entities are further genodermatoses which may involve the neck. In our review we have integrated inherited dermatoses which do not obligatorily affect the neck but have been well documented to do so. Our work should give the clinician a checklist on genodermatoses which may produce reticulate and mottled pigmentation on the neck.

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“…Das gleichzeitige Vorkommen dieser beiden Erkrankungen ist in der Literatur erst wenige Male beschrieben worden [9,10,11,12], und man nimmt an, dass diese Koinzidenz nicht zufällig ist. Das gleichzeitige Vorkommen dieser beiden Erkrankungen ist in der Literatur erst wenige Male beschrieben worden [9,10,11,12], und man nimmt an, dass diese Koinzidenz nicht zufällig ist.…”

Section: Die Retikuläre Pigmentdermatose Derunclassified

Retikuläre Pigmentdermatose der Beugen

2001

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Reticulated pigmented anomaly of the flexures (Dowling-Degos disease) is a rare autosomal-dominant genodermatosis with variable penetrance that is characterized by reticulated hyperpigmentation of the flexures. Acne inversa has been previously described in the literature under several synonyms, such as acne triad, acne tetrad and hidradenitis suppurativa. Acne inversa is an inflammation affecting the pilosebaceous units of the flexures. We report a case of Dowling-Degos disease in association with acne inversa. The association of these diseases has been described several times and it appears not to be coincidental. Pathogenetic mechanisms leading to this coincidence are discussed.

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Dowling-Degos disease associated with hidradenitis suppurativa

Abstract: A case of Dowling-Degos disease coexisting with hidradenitis suppurativa is described. We propose that the follicular occlusion inherent in Dowling-Degos disease may predispose to the development of hidradenitis suppurativa.

Cited by 45 publications

References 7 publications

Hidradenitis suppurativa

Hidradenitis suppurativa

Genodermatosis with Reticulate, Patchy and Mottled Pigmentation of the Neck – A Clue to Rare Dermatologic Disorders

Retikuläre Pigmentdermatose der Beugen

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