Dosimetric investigation of accelerated partial breast irradiation (APBI) using CyberKnife

Abstract

The dosimetric feasibility of APBI using CyberKnife was investigated in this retrospective study. All the dosimetric parameters strictly met the guidelines from the NSABP B39∕RTOG 0413 protocol. With advanced real-time tracking capability, CyberKnife should provide better target coverage and spare nearby critical organs for APBI treatment.

2016 ESC Position Paper on cancer treatments and cardiovascular toxicity developed under the auspices of the ESC Committee for Practice Guidelines

“…To reduce the cardiac radiation dose during radiotherapy, the following techniques and strategies have been described: The deep inspiration breath‐hold technique, or respiratory gating, allowing shielding of the heart from tangential fields and reduction of radiation to organs at risk without compromising clinical target volume Multiple or rotational sources of radiation beams (photons/electrons). Linear accelerator photons allowing treatment of patients with equal weighting of anterior and posterior portals, with subcarinal block and the shrinking field technique. Intensity‐modulated radiation beams using multileaf collimators are superior to partial shielding. Reporting and minimization of radiation doses received by normal tissue Tracking systems, consisting of a small linear particle accelerator mounted on a general purpose industrial robot with a robotic arm, allowing the energy to be directed at any part of the body from any location.…”

“…The robotic mounting through a complex imaging system and software allows very fast repositioning of the source and adaptation of radiation delivery, according to patient movement and cancer modification, with an accuracy of 0.5 mm. This method of radiotherapy treatment resembles a surgical treatment and is also called ‘radiosurgery’ …”

2016 ESC Position Paper on cancer treatments and cardiovascular toxicity developed under the auspices of the ESC Committee for Practice Guidelines

“…Ta metoda radioterapii przypomina leczenie chirurgiczne i jest określana mianem "radiochirurgii" [295].…”

Stereotactic Accelerated Partial Breast Irradiation for Early-Stage Breast Cancer: Rationale, Feasibility, and Early Experience Using the CyberKnife Radiosurgery Delivery Platform

“…CyberKnife stereotactic accelerated partial breast irradiation (CK-SAPBI) offers technical improvements in partial breast irradiation using real-time tracking, respiratory motion management, and submillimeter accuracy with few technical limitations ( 18 , 19 ). Reduced target and treatment uncertainty allows for treatment intensification, maximal target coverage reminiscent of high-dose brachytherapy while protecting normal breast tissue from unnecessary high-dose irradiation ( 20 – 22 ). With these technical improvements, we expect more women will be eligible for CK-SAPBI with similar local control, increased patient convenience, and improved cosmesis compared to existing EB-APBI techniques.…”