volume 7, issue 1, P25-32 2000
DOI: 10.1016/s0928-4680(99)00034-6
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R.B Scott, K.S Reddy, K Husain, E.C Schlorff, L.P Rybak, S.M Somani

Abstract: This study investigated the alterations in levels of glutathione, lipid peroxidation, and antioxidant enzyme activity in the liver, lung, and kidney of rats treated with acute doses of ethanol. Male Fisher-344 rats were randomly divided into four groups, and were treated as follows: (1) vehicle (saline) control; (2) ethanol 2 g/kg, p.o.; (3) ethanol 4g/kg, p.o.; and (4) ethanol 6 g/kg, p.o. The animals were sacrificed 1 h after treatment, and tissues were isolated and analyzed. The hepatic GSH levels significa…

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