Dose-free monitoring of radiotherapy treatments with scattered photons: First experimental results at a 6-MV Linac

Simoes, Hugo; Pinto, M.; Cunha, Micaela; Gonçalves, Joana; Sampaio, Liliana; Ferreira, Ricardo B.; Saraiva, Henrique M.; Barbeiro, A.R.; Capela, M.; Ferreira, B.; Fonte, P.; Ghithan, Sharif; Leal, Antonio; Lopes, Maria do Carmo; Martins, P.A.F.; Crespo, Paulo

doi:10.1109/nssmic.2011.6153827

Cited by 2 publications

(2 citation statements)

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“…Compton scatter imaging is a well‐studied modality in the context of tomographic imaging and other quantitative modalities . While its application in a clinical setting has so far not materialized, in the context of tumor tracking several promising proposals are currently being pursued that make use of the radiation scattered by the patient during the treatment, either using the megavoltage x‐ray beam as the source of the scattered radiation or a kilovoltage fan beam to obtain a cross‐sectional view of the patient, in both works employing pinhole or multihole collimators to form the image. In this work, we have shown that the radiation scattered by the patient when irradiated with an imaging kilovoltage x‐ray beam can be used in conjunction with the obtained primary image to determine spatial information about internal objects in the imaged subject.…”

Section: Discussionmentioning

confidence: 99%

Directional scatter imaging for the stereoscopic tracking of fiducial markers in a single kV exposure

Garnica-Garza

2017

Medical Physics

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Section: Discussionmentioning

confidence: 99%

Directional scatter imaging for the stereoscopic tracking of fiducial markers in a single kV exposure

Garnica-Garza

2017

Medical Physics

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“…1) [6], [7], [8], and (2) low-dose morphologic imaging, mainly on-board imaging for assisting RT (OrthoCT concept, not addressed here) [8], [9]. It consists in detecting the radiation that escapes a patient -being irradiatedat right angles in respect to the photon beam axis.…”

Section: Introductionmentioning

confidence: 99%

Observation of tumor morphological changes in lung irradiation with orthogonal ray imaging: RTmonitoring - A simulation study

Simoes

Bravo

Capela

et al. 2013

2013 IEEE Nuclear Science Symposium and Medical Imaging Conference (2013 NSS/MIC)

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Orthogonal ray imaging is a new potential technique that consists in detecting radiation dispersed in the patient and emitted perpendicularly to the beam axis. RTmonitoring aims at real time radiotherapy (RT) monitoring. OrthoCT addresses lowdose patient morphologic imaging, mainly on-board for assisting RT (not studied here). We report Geant4 simulations analyzing the capability of RTmonitoring to detect (1) a lung tumor deviation of 9.36 mm, (2) a tumor shrinkage of 9.36 mm, and (3) a tumor growth of 30 mm. The original spherical tumor has the density of water and a diameter of ca 30 mm. In RT treatment planning security margins are added around the tumor to be irradiated in order to account for these and other RT disturbing mechanisms. Here, despite not addressing a real treatment plan, we simulate the aforementioned tumor morphological changes to investigate whether an RTmonitoring system can be useful in detecting such changes. Indeed, tumor dislocation/modification in the lung represents a topic of strong research and development worldwide for all forms of RT. A beam missing the dislocated tumor will represent an underdosage that may be strongly correlated with tumor relapse. On the other hand, the detection of tumor shrinkage in lung RT may allow for a reduction of the dose field, which represents an important relief of the dose burden to the surrounding healthy lung. It is known that healthy Manuscript lung tissue subjected to RT doses result at times in fibrosis which impairs respiratory function. Finally, detection of tumor growth represents equally an important asset in RT due to the evident tumor underdosage if such scenario is missed. We show that the counts distributions obtained with RTmonitoring result in a very high visual correlation both with the simulated, original dose distribution, and with the tumor location. Therefore, this technique is likely to represent a high potential asset for imageguided RT, adaptive RT, and real-time RT dose verification.

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Dose-free monitoring of radiotherapy treatments with scattered photons: First experimental results at a 6-MV Linac

Cited by 2 publications

References 8 publications

Directional scatter imaging for the stereoscopic tracking of fiducial markers in a single kV exposure

Directional scatter imaging for the stereoscopic tracking of fiducial markers in a single kV exposure

Observation of tumor morphological changes in lung irradiation with orthogonal ray imaging: RTmonitoring - A simulation study

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