DOP87 Multi-parameter datasets are required to identify the true prevalence of IBD: The Lothian IBD Registry (LIBDR)

Jones, G. R.; Lyons, Mathew; Plevris, Nikolas; Jenkinson, P; Bisset, Cathy; Fulforth, James; Chuah, Cher Shiong; Minnis, Sarah; Gillespie, S-L; Brindle, William; Burgess, Christopher; Henderson, Paul; Wilson, DC; Lees, C

doi:10.1093/ecco-jcc/jjy222.121

Cited by 4 publications

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“…This study has examined in detail the UK epidemiology of ulcerative colitis and Crohn's Disease using a large, population‐based dataset. Previous reports of the epidemiology of ulcerative colitis and Crohn's disease in the UK have used comparatively small datasets or focused on regional areas which may not be generalisable to the UK population as a whole or are now largely historic 9,11,12 . As with other high‐prevalence areas, 3,4 this study shows that ulcerative colitis and Crohn's disease prevalence in the UK have been increasing over the past two decades at a rate of 2%‐3% per annum.…”

Section: Discussionmentioning

confidence: 72%

“…Given the individual and societal impact of these diseases, accurate and up‐to‐date data on prevalence and outcomes are important for service planning. Published United Kingdom (UK) inflammatory bowel disease epidemiology data are out of date or based on small or regional datasets which may not be representative of the United Kingdom as a whole 4,9‐12 …”

Section: Introductionmentioning

confidence: 99%

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Changing patterns in the epidemiology and outcomes of inflammatory bowel disease in the United Kingdom: 2000‐2018

King

Reulen

Thomas

et al. 2020

Aliment Pharmacol Ther

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Background: Data regarding incidence, prevalence and long-term outcomes of inflammatory bowel diseases in the UK are limited or outdated. Aims:To investigate incidence and prevalence of Crohn's disease and ulcerative colitis and risk of colorectal cancer and all-cause mortality in these diseases.Methods: Inflammatory bowel disease cases between 2000 and 2018 were identified from a national primary care database. Inflammatory bowel disease prevalence was forecast until 2025. The association between inflammatory bowel disease and colorectal cancer and all-cause mortality was investigated using age/sex-matched retrospective cohort studies. Hazard ratios were adjusted for age, sex, deprivation, comorbidity, smoking status and body mass index.Results: Ulcerative colitis prevalence increased from 390 to 570 per 100 000 population from 2000 to 2017. Prevalence of Crohn's disease increased from 220 to 400 per 100 000. In 2017 male Crohn's disease prevalence was 0.35% (95% confidence interval 0.34-0.36); female prevalence was 0.44% (0.43-0.45). Prevalence of inflammatory bowel disease is predicted to be 1.1% by 2025. Incidence of ulcerative colitis and Crohn's disease was 23.2 (22.8-23.6) and 14.3 (14.0-14.7) per 100 000 person-years respectively. Subjects with ulcerative colitis were more likely to develop colorectal cancer than controls (adjusted Hazard Ratio 1.40 [1.23-1.59]). Colorectal cancer rates remained stable in inflammatory bowel diseases over time. Ulcerative colitis and Crohn's disease were associated with increased risk of all-cause mortality (1.17 [1.14-1.21] and 1.42 [1.36-1.48] respectively). Conclusions: The UK prevalence of inflammatory bowel disease is greater than previous reports suggest and we predict an 11% increase in prevalence by the year 2025. Mortality risk in inflammatory bowel disease and colorectal cancer risk in ulcerative colitis are increased compared to matched controls. | 923 KING et al. Studies reporting increased mortality riskStudies reporting decrease/equivalent mortality risk Crohn's Disease Ulcerative Colitis Crohn's Disease Ulcerative ColitisAbbreviations: HR, hazard ratio; SMR, standardised mortality ratio.

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Section: Discussionmentioning

confidence: 72%

Section: Introductionmentioning

confidence: 99%

Changing patterns in the epidemiology and outcomes of inflammatory bowel disease in the United Kingdom: 2000‐2018

King

Reulen

Thomas

et al. 2020

Aliment Pharmacol Ther

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“…Over 500 000 people in the UK are estimated to be affected by inflammatory bowel disease (IBD) 1 2. As lifelong, relapsing and complex conditions, medical costs associated with the care of the principal forms of IBD (Crohn’s disease and ulcerative colitis) can be comparable with those for major chronic diseases such as diabetes mellitus and cancer.…”

Section: Introductionmentioning

confidence: 99%

Consensus standards of healthcare for adults and children with inflammatory bowel disease in the UK

Kapasi

Glatter

Lamb

et al. 2019

Frontline Gastroenterol

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ObjectiveSymptoms and clinical course during inflammatory bowel disease (IBD) vary among individuals. Personalised care is therefore essential to effective management, delivered by a strong patient-centred multidisciplinary team, working within a well-designed service. This study aimed to fully rewrite the UK Standards for the healthcare of adults and children with IBD, and to develop an IBD Service Benchmarking Tool to support current and future personalised care models.DesignLed by IBD UK, a national multidisciplinary alliance of patients and nominated representatives from all major stakeholders in IBD care, Standards requirements were defined by survey data collated from 689 patients and 151 healthcare professionals. Standards were drafted and refined over three rounds of modified electronic-Delphi.ResultsConsensus was achieved for 59 Standards covering seven clinical domains; (1) design and delivery of the multidisciplinary IBD service; (2) prediagnostic referral pathways, protocols and timeframes; (3) holistic care of the newly diagnosed patient; (4) flare management to support patient empowerment, self-management and access to specialists where required; (5) surgery including appropriate expertise, preoperative information, psychological support and postoperative care; (6) inpatient medical care delivery (7) and ongoing long-term care in the outpatient department and primary care setting including shared care. Using these patient-centred Standards and informed by the IBD Quality Improvement Project (IBDQIP), this paper presents a national benchmarking framework.ConclusionsThe Standards and Benchmarking Tool provide a framework for healthcare providers and patients to rate the quality of their service. This will recognise excellent care, and promote quality improvement, audit and service development in IBD.

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2019

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DOP87 Multi-parameter datasets are required to identify the true prevalence of IBD: The Lothian IBD Registry (LIBDR)

Cited by 4 publications

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Changing patterns in the epidemiology and outcomes of inflammatory bowel disease in the United Kingdom: 2000‐2018

Changing patterns in the epidemiology and outcomes of inflammatory bowel disease in the United Kingdom: 2000‐2018

Consensus standards of healthcare for adults and children with inflammatory bowel disease in the UK

UEG Week 2019 Poster Presentations

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