volume 56, issue 2, P149-151 2012
DOI: 10.1590/s0004-27302012000200009
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Abstract: False-negative result of highly sensitive thyroglobulin INTRODUCTION M easurement of serum thyroglobulin (Tg) is considered to be the most sensitive method for the detection of persistent or recurrent disease in patients with differentiated thyroid carcinoma after initial therapy. Obviously, the sensitivity of this marker is limited in patients with poorly differentiated tumors that do not secrete Tg, or in patients with circulating anti-thyroglobulin antibodies (TgAb) that interfere with serum Tg measurement…

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