Arthritis Res Ther 2018 DOI: 10.1186/s13075-018-1553-8 View full text
L. E. Burgers, D. M. Boeters, M. Reijnierse, A. H. M. van der Helm-van Mil

Abstract: BackgroundAlthough infrequent, some rheumatoid arthritis (RA) patients achieve disease-modifying antirheumatic drug (DMARD)-free sustained remission. The absence of RA-specific autoantibodies, such as anticitrullinated protein antibodies (ACPA), is known to be associated with this outcome but further mechanisms underlying the chronic nature of RA are largely unknown. Magnetic resonance imaging (MRI)-detected bone marrow edema (BME), or osteitis, strongly predicts erosive progression and is associated with ACPA…

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