Does the Brown classification of maxillectomy defects have prognostic prediction for patients with oral cavity squamous cell carcinoma involving the maxilla?

Sun, Qian; Zhang, W.-B.; Гао, Мін; Yu, Shanhe; Mao, Chi; Guo, Chuanbin; Yu, Guang; Peng, Xin

doi:10.1016/j.ijom.2020.01.021

Cited by 6 publications

(10 citation statements)

References 29 publications

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“…An overview of all the included studies and their characteristics is presented in Table 1 [2,[9][10][11][12][13][14][15][16][17][18][19][20][21][22][23][24][25][26][27]. All 20 included studies were observational.…”

Section: Study Characteristicsmentioning

confidence: 99%

“…Treatment modalities of 1185/1531 (77%) patients were specified and 346/1531 (23%) were not [12,16,21,24]. Nine different treatment modalities were reported: 748/1185 (63%) patients had surgery only, 277/1185 (23%) had surgery with postoperative radiotherapy, 51/1185 (4%) had surgery with postoperative (chemo)radiotherapy, 40/1185 (3%) had preoperative intra-arterial chemotherapy with radiotherapy and surgery, 10/1185 (0.8%) had preoperative intravenous chemotherapy with radiotherapy and surgery, 3/1185 (0.3%) had preoperative radiotherapy with surgery, 27/1185 (2%) had no surgery and chemoradiotherapy, 19/1185 (2%) had no surgery and radiotherapy only, and 10/1185 (0.8%) patients had palliative treatment.…”

Section: Study Characteristicsmentioning

confidence: 99%

“…Advanced tumour stage [11,13,14,19,20,[22][23][24], close/positive surgical margins (after reresection) [11, 13-15, 19, 22-24], cervical lymph node involvement [13][14][15]19], extracapsular spread [13][14][15]20], bone/vascular/perineural invasion and non-cohesive growth [19,20,22]. The indication for postoperative radiotherapy was not specified for 104/259 (40%) patients [9,10,17,18,25].…”

Section: Study Characteristicsmentioning

confidence: 99%

“…Various factors were correlated with OS (Table 4). Age [2,20], advanced tumour stage (T3-4) [10,17,22,24,25] and positive surgical margins [2, 11-13, 17, 20, 25] were all correlated with decreased OS rates in multiple studies.…”

Section: Risk Factors -Osmentioning

confidence: 99%

“…Moreover, tumour involvement of the nasal fossa, maxillary sinus and orbital floor was also correlated with decreased OS rates [20]. One study demonstrated that significant postoperative midfacial defects are also associated with reduced OS rates [24].…”

Section: Risk Factors -Osmentioning

confidence: 99%

See 4 more Smart Citations

Local recurrence and survival after treatment of oral squamous cell carcinoma of the maxilla: A systematic review and meta-analysis

Slieker¹,

Rombout²,

Bree³

et al. 2022

Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology

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Section: Study Characteristicsmentioning

confidence: 99%

Section: Study Characteristicsmentioning

confidence: 99%

Section: Study Characteristicsmentioning

confidence: 99%

Section: Risk Factors -Osmentioning

confidence: 99%

Section: Risk Factors -Osmentioning

confidence: 99%

See 3 more Smart Citations

Local recurrence and survival after treatment of oral squamous cell carcinoma of the maxilla: A systematic review and meta-analysis

Slieker¹,

Rombout²,

Bree³

et al. 2022

Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology

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Changing trends in the microvascular reconstruction and oral rehabilitation following maxillary cancer

Rogers

Adatia²,

Hackett³

et al. 2022

Eur Arch Otorhinolaryngol

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Purpose The maxillectomy defect is complex and the best means to achieve optimal reconstruction, and dental rehabilitation is a source of debate. The refinements in zygomatic implant techniques have altered the means and speed by which rehabilitation can be achieved and has also influenced the choice regarding ideal flap reconstruction. The aim of this study is to report on how the method of reconstruction and oral rehabilitation of the maxilla has changed since 1994 in our Institution, and to reflect on case mix and survival. Methods Consecutive head and neck oncology cases involving maxillary resections over a 27-year period between January 1994 and November 2020 were identified from hospital records and previous studies. Case note review focussed on clinical characteristics, reconstruction, prosthetic rehabilitation, and survival. Results There were 186 patients and the tumour sites were: alveolus for 56% (104), hard palate for 19% (35), maxillary sinus for 18% (34) and nasal for 7% (13). 52% (97) were Brown class 2 defects. Forty-five patients were managed by obturation and 78% (142/183) had free tissue transfer. The main flaps used were radial (52), anterolateral thigh (27), DCIA (22), scapula (13) and fibula (11). There were significant changes over time regarding reconstruction type, use of primary implants, type of dental restoration, and length of hospital stay. Overall survival after 24 months was 64% (SE 4%) and after 60 months was 42% (SE 4%). Conclusion These data reflect a shift in the reconstruction of the maxillary defect afforded by the utilisation of zygomatic implants.

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Squamous cell carcinoma of the conjunctiva. Case report

García

Arenas

Gubbay

et al. 2022

International Journal of Surgery Case Reports

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Does the Brown classification of maxillectomy defects have prognostic prediction for patients with oral cavity squamous cell carcinoma involving the maxilla?

Cited by 6 publications

References 29 publications

Local recurrence and survival after treatment of oral squamous cell carcinoma of the maxilla: A systematic review and meta-analysis

Local recurrence and survival after treatment of oral squamous cell carcinoma of the maxilla: A systematic review and meta-analysis

Changing trends in the microvascular reconstruction and oral rehabilitation following maxillary cancer

Squamous cell carcinoma of the conjunctiva. Case report

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