Does pregnancy have any impact on long term damage accrual and on the outcome of lupus nephritis?

Gianfreda, Davide; Quaglini, Silvana; Frontini, Giulia; Raffiotta, Francesca; Moroni, Gabriella

doi:10.1016/j.jaut.2017.06.003

“…Likewise, the effect of pregnancy on CKD progression is not fully understood because of different study designs, obstetric policies, and duration of follow-up. Overall, short-and long-term decrease in kidney function is unusual in early CKD, but the risk increases as CKD severity increases [6,7,[38][39][40][41][44][45][46][47][48].…”

Section: Chronic Kidney Diseasementioning

confidence: 99%

“…Due to the high heterogeneity of CKD, we do not know if and how pregnancy outcomes are modulated by the different nephropathies, as besides the most common ones such as IgA or lupus nephropathy, diabetic nephropathy, and reflux nephropathy, evidence is scant [44,45,[112][113][114]. How should we define preconception risks of pregnancy with respect to current proteinuria cut offs?…”

Section: Present and Future What We Do Not Knowmentioning

confidence: 99%

What we do and do not know about women and kidney diseases; questions unanswered and answers unquestioned: reflection on World Kidney Day and International Women’s Day

Piccoli

¹

,

Alrukhaimi

²

,

Liu

³

et al. 2018

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Chronic Kidney Disease affects approximately 10% of the world's adult population: it is within the top 20 causes of death worldwide, and its impact on patients and their families can be devastating. World Kidney Day and International Women's Day in 2018 coincide, thus offering an opportunity to reflect on the importance of women's health and specifically their kidney health, on the community, and the next generations, as well as to strive to be more curious about the unique aspects of kidney disease in women so that we may apply those learnings more broadly. Girls and women, who make up approximately 50% of the world's population, are important contributors to society and their families. Gender differences continue to exist around the world in access to education, medical care, and participation in clinical studies. Pregnancy is a unique state for women, offering an opportunity for diagnosis of kidney disease, but also a state where acute and chronic kidney diseases may manifest, and which may impact future generations with respect to kidney health. There are various autoimmune and other conditions that are more likely to impact women with profound consequences for child bearing, and on the fetus. Women have different complications on dialysis than men, and are more likely to be donors than recipients of kidney transplants. In this editorial, we focus on what we do and do not know about women, kidney health, and kidney disease, and what we might learn in the future to improve outcomes worldwide.

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“…Влияние беременности на прогрессирование ХБП не вполне ясно, поскольку дизайн, акушерская тактика и продолжительность наблюдения в проведенных исследованиях разли-чались. В целом известно, что непосредственное и отдаленное снижение функции почек, ассоции-рованное с беременностью, несвойственно ранним стадиям ХБП, но по мере усугубления тяжести ХБП риск ее прогрессирования возрастает [6,7,[38][39][40][41][44][45][46][47][48].…”

Section: что мы знаемunclassified

“…Доказательства, помимо каса-ющихся наиболее распространенных нефропатий, таких как IgA-нефропатия, волчаночный нефрит, диабетическая нефропатия и рефлюкс-нефропатия, крайне скудны [44,45,[112][113][114]. Как следует опреде-лять предгравидарные риски беременности в свете пороговых значений протеинурии?…”

Section: настоящее и будущее: чего мы не знаемunclassified

What we do and do not know about women and kidney diseases; questions unanswered and answers unquestioned: Reflection on World Kidney Day and International Woman’s Day

Piccoli

¹

,

Alrukhaimi

²

,

Liu

³

et al. 2018

View full text Add to dashboard Cite

“…Likewise, the effect of pregnancy on CKD progression is not fully understood because of different study designs, obstetric policies, and duration of follow-up. Overall, short-and long-term decrease in kidney function is unusual in early CKD, but the risk increases as CKD severity increases (6,7,(38)(39)(40)(41)(44)(45)(46)(47)(48).…”

Section: Chronic Kidney Diseasementioning

confidence: 99%

Untitled

2018

Turk Neph Dial Transpl

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Chronic Kidney Disease affects approximately 10% of the world's adult population: it is within the top 20 causes of death worldwide, and its impact on patients and their families can be devastating. World Kidney Day and International Women's Day in 2018 coincide, thus offering an opportunity to reflect on the importance of women's health and specifically their kidney health, on the community, and the next generations, as well as to strive to be more curious about the unique aspects of kidney disease in women so that we may apply those learnings more broadly.Girls and women, who make up approximately 50% of the world's population, are important contributors to society and their families. Gender differences continue to exist around the world in access to education, medical care, and participation in clinical studies. Pregnancy is a unique state for women, offering an opportunity for diagnosis of kidney disease, but also a state where acute and chronic kidney diseases may manifest, and which may impact future generations with respect to kidney health. There are various autoimmune and other conditions that are more likely to impact women with profound consequences for child bearing, and on the fetus. Women have different complications on dialysis than men, and are more likely to be donors than recipients of kidney transplants.In this editorial, we focus on what we do and do not know about women, kidney health, and kidney disease, and what we might learn in the future to improve outcomes worldwide. KEY WORDS:Women, Access to care, Kidney health, Acute and chronic kidney disease, Inequities ÖZ Kronik Böbrek Hastalığı dünyadaki erişkin popülasyonun yaklaşık %10'unu etkiler: dünya çapında ölümün en sık görülen 20 nedeninden biridir ve hastalar ile aileleri üzerinde çok ciddi etkileri olabilir. Dünya Böbrek Günü ve Uluslararası Kadınlar Günü 2018 yılında aynı güne denk gelmiştir. Böylece kadın sağlığı ve özellikle böbrek sağlığının toplum ve sonraki nesiller üzerindeki önemini düşünmek, öğrendiklerimizi daha geniş bir şekilde uygulayabilmek için böbrek hastalığının benzersiz yönleri konusunda daha meraklı olmaya çalışmak için bir fırsat sunmaktadır.Dünya nüfusunun yaklaşık %50'sini oluşturan kızlar ve kadınlar toplum ve ailelerine önemli katkılar yaparlar. Dünya çapında eğitime erişim, tıbbi bakım ve klinik çalışmalara katılmada cinsiyetle ilgili farklılıklar bulunmaya devam etmektedir. Hamilelik kadınlar için eşsiz bir dönemdir ve böbrek hastalığına tanı konması fırsatı yaratır ama aynı zamanda böbrek sağlığı açısından gelecek nesilleri etkileyebilecek akut ve kronik böbrek hastalıklarının ortaya çıkabileceği bir durumdur. Kadınları etkilemesi daha olası olan ve çocuk sahibi olma ve fetus üzerinde çok önemli sonuçlar doğurabilecek çeşitli otoimmün ve başka hastalıklar bulunmaktadır. Kadınların diyaliz komplikasyonları erkeklerden farklıdır ve böbrek naklinde alıcı olmak yerine verici olma olasılıkları daha yüksektir.Bu editör yazısında kadınlar, böbrek sağlığı ve böbrek hastalığı hakkında bildiklerimiz ve bilmed...

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Does pregnancy have any impact on long term damage accrual and on the outcome of lupus nephritis?

Cited by 42 publications

References 29 publications

What we do and do not know about women and kidney diseases; questions unanswered and answers unquestioned: reflection on World Kidney Day and International Women’s Day

What we do and do not know about women and kidney diseases; questions unanswered and answers unquestioned: reflection on World Kidney Day and International Women’s Day

What we do and do not know about women and kidney diseases; questions unanswered and answers unquestioned: Reflection on World Kidney Day and International Woman’s Day

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