1988
DOI: 10.1055/s-2007-1020078 View full text |Buy / Rent full text
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Abstract: During 1986, 343 consecutive patients who underwent isolated coronary bypass grafting were given 10 mg of propranolol three times daily for six postoperative weeks to help prevent supraventricular tachyarrhythmias. The incidence of these arrhythmias in this group was compared to that in a similar group of 337 consecutive patients who underwent coronary surgery in 1984 at the same institution and did not receive propranolol. There was no significant difference in the overall incidence of such arrhythmias betwee… Show more

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“…Some clinical trials using β-adrenergic antagonists have demonstrated prophylactic benefit in postoperative AF 21 23 ; however, other studies showed conflicting conclusions. 16 , 24 , 25 A possible reason for this difference may be that in some studies, patients randomly assigned to placebo were treated with β-adrenergic blockers until the time of surgery. 11 According to the American College of Cardiology/American Heart Association and the European Society of Cardiology Guidelines for AF, the preoperative or early postoperative administration of β-blockers in patients without contraindications is evidence for preventing AF after CABG surgery.…”
Section: Discussionmentioning
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“…Some clinical trials using β-adrenergic antagonists have demonstrated prophylactic benefit in postoperative AF 21 23 ; however, other studies showed conflicting conclusions. 16 , 24 , 25 A possible reason for this difference may be that in some studies, patients randomly assigned to placebo were treated with β-adrenergic blockers until the time of surgery. 11 According to the American College of Cardiology/American Heart Association and the European Society of Cardiology Guidelines for AF, the preoperative or early postoperative administration of β-blockers in patients without contraindications is evidence for preventing AF after CABG surgery.…”
Section: Discussionmentioning