Does higher body mass index contribute to worse asthma control in an urban population?

Clerisme-Beaty, Emmanuelle; Karam, Sabine; Rańd, Cynthia S.; Patino, Cecilia María; Bilderback, Andrew; Riekert, Kristin A.; Okelo, Sande O.; Diette, Gregory B.

doi:10.1016/j.jaci.2009.05.034

Cited by 45 publications

(41 citation statements)

References 36 publications

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“…On the other hand, Clerisme-Beaty et al 21 performed a cross sectional assessment of asthma control in 292 patients with asthma. The majority were women (82%) and African-American (63%), recruited from primary care using 4 different validated survey tools: the Asthma Control and Communication Instrument, the Asthma Control Test, the ACQ, and the Asthma Therapy Assessment Questionnaire.…”

Section: Obesity and Asthma Controlmentioning

confidence: 99%

Obesity and Asthma: Impact on Severity, Asthma Control, and Response to Therapy

Juel

Ulrik

2012

Respir Care

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Asthma is more prevalent in obese, compared with normal weight, subjects. Our aim has been to review current knowledge of the impact of obesity on asthma severity, asthma control, and response to therapy. Several studies have shown that overweight and obesity is associated with more severe asthma and impaired quality of life, compared with normal weight individuals. Furthermore, obesity is associated with poorer asthma control, as assessed by asthma control questionnaires, limitations in daily activities, breathlessness and wheezing, use of rescue medication, unscheduled doctor visits, emergency department visits, and hospitalizations for acute asthma. Studies of the impact of a high body mass index on response to asthma therapy have, however, revealed conflicting results. Most studies show that overweight and obesity is associated with less favorable response to asthma therapy, with regard to symptoms, level of FEV 1 , fraction of exhaled nitric oxide, and airway responsiveness. Some studies suggest that asthma in the obese patient might be more responsive to leukotriene modifiers, orchestrated by leptin and/or adiponectin derived from adipose tissue, than to inhaled corticosteroids, possibly reflecting differences in the underlying airway inflammation in obese versus non-obese asthmatics. In conclusion, overweight and obesity is associated with poorer asthma control and, very importantly, overall poorer response to asthma therapy, compared with normal weight individuals.

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Section: Obesity and Asthma Controlmentioning

confidence: 99%

Obesity and Asthma: Impact on Severity, Asthma Control, and Response to Therapy

Juel

Ulrik

2012

Respir Care

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“…However, there are contradictory results in both adult and childhood researches about the association of obesity with severity of asthma (2)(3)(4)(5)(6). Some report that obesity increases asthma symptom and severity while some report that obesity does not have a significant influence on asthma severity and control (3)(4)(5)(6).…”

Section: Introductionmentioning

confidence: 99%

Is Obesity Related to Worse Control in Children with Asthma?

Yılmaz

Söğüt²,

Bozgül³

et al. 2014

Tuberk Toraks

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“…Higher BMI also led to lower scores on the Asthma Quality of Life Questionnaire 31 . Other studies also study showed that normal-weight had a better asthma control versus obese and overweight patients 32,33 . Similarly, the drug response to asthma medications also vary by the BMI.…”

Section: Obesity and Asthma Managementmentioning

confidence: 91%

Asthma and Obesity - the Recent Advancements

Bharadwaj

Verma

Deshkar

et al. 2015

MVP Journal of Medical Science

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The incidence of obesity and asthma is increasing globally. Evidence shows that there is a correlation between the two, both epidemiologically and pathophysiologically. The inflammatory link between the two is now being established as obesity is a risk factor for asthma and also plays an important role in its prevention and management. Evidence shows that patients with metabolic disorders such as insulin resistance may be at an increased risk for asthma, however the exact pathophysiology of the same remains unknown. We hereby present an overview of the recent advancement in this field.

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Does higher body mass index contribute to worse asthma control in an urban population?

Abstract: Background-Epidemiologic findings support a positive association between asthma and obesity.

Cited by 45 publications

References 36 publications

Obesity and Asthma: Impact on Severity, Asthma Control, and Response to Therapy

Obesity and Asthma: Impact on Severity, Asthma Control, and Response to Therapy

Is Obesity Related to Worse Control in Children with Asthma?

Asthma and Obesity - the Recent Advancements

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