Does Gastric Dilatation Limit the Success of Sleeve Gastrectomy as a Sole Operation for Morbid Obesity?

Langer, Felix B.; Bohdjalian, Arthur; Felberbauer, F. X.; Fleischmann, Edith; Hoda, Mir Ali Reza; Ludvik, Bernhard; Zacherl, Johannes; Jakesz, R.; Prager, Gerhard

doi:10.1381/096089206775565276

Cited by 208 publications

(127 citation statements)

References 42 publications

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“…In human beings, the failure of weight lost after SG has been explained by the dilatation of the stomach. Langer has observed gastric dilatation with contrast-enhanced upper GIS series in one patient, and weight gain after weight lost in 3 out of 23 patients in 12 months [22]. In rats, postmortem examinations revealed that the dilation of resected gastric tissue reached nearly normal size, and dilatation of remnant gastric tissue in SG has been also observed in our study (Fig.…”

Section: Discussionsupporting

confidence: 86%

Hematological, Biochemical, and Immunological Laboratory and Histomorphological Effects of Sleeve Gastrectomy on Female Rats

et al. 2013

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Restriction of food intake leads to immunologic and histomorphological changes in rats demonstrated by Moriyama. This study is planned to show how sleeve gastrectomy restricts food intake and its effects on biochemical liver function, immunologic and hematologic laboratory parameters, and histomorphological changes in rats. We used sleeve gastrectomy model on seven young adult female rats and compared study group with sham and control groups. Food consumption of rats was measured. All rats were sacrificed on the 50th day, and blood and tissue samples were collected. There was a significant low food intake in sleeve gastrectomy group (p=0.013). No differences were observed on hematologic, biochemical, and immunologic laboratory parameters between groups. Toxicity parameters in liver samples such as cytoplasmic atrophy, single-cell hepatocellular necrosis, and necrotic eosinophilic cells were significantly high in sleeve gastrectomy group (p=0.005). Histomorphological examination of the spleen and kidneys revealed significant changes in sleeve gastrectomy and sham groups compared with controls (p=0.004 and p=0.018, respectively). Although sleeve gastrectomy does not lead to alteration in hematologic, biochemical, and immunologic laboratory parameters, it causes decreased food consumption, which results in toxicological histomorphological changes in rat liver as well as some changes in kidney and spleen samples.

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Section: Discussionsupporting

confidence: 86%

Hematological, Biochemical, and Immunological Laboratory and Histomorphological Effects of Sleeve Gastrectomy on Female Rats

et al. 2013

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“…The surgical complications most commonly encountered are: fistula, which usually occurs at the angle Table 2 Table 2 Table 2 Table 2 Table 2 Table 3 Table 3 Table 3 Table 3 Table 3 Table 4 Table 4 Table 4 Table 4 Table 4 Distribution of patients according to the quality of life after treatment. of Hiss, is difficult to treat, with an incidence ranging from 0.7 to 5.3% 14,17 ; stenosis, especially in the angular notch, due to failure when preparing the gastric tube 27 ; portals infection; hernia; cholelithiasis 3.8% 15; gastroesophageal reflux disease 28,29 ; and dilatation of the gastric pouch after two years of operation and weight regain 15,28,30,31 . The reduction of the stomach promotes reduced food intake and reduced parietal cells, resulting in decreased production of hydrochloric acid, which is important in the absorption of iron.…”

Section: Discussion Discussion Discussion Discussionmentioning

confidence: 99%

“…Among the causes of regained weight we can highlight two main technical mistakes while performing the operation: use of catheters with diameter greater than 32 Fr. to calibrate the stomach and no resecting the antral region, initiating the gastroplasty at the great gastric curvature more than six cm from the pylorus 20,25,30,31 . We understand that the approach to obesity should not just be restricted to surgical treatment.…”

Section: Discussion Discussion Discussion Discussionmentioning

confidence: 99%

Avaliação da qualidade de vida tardia após gastroplastia vertical

Pimenta

Moura

Filho³

et al. 2013

Rev. Col. Bras. Cir.

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Long-term quality of life after vertical sleeve gastroplasty Long-term quality of life after vertical sleeve gastroplasty Long-term quality of life after vertical sleeve gastroplasty Long-term quality of life after vertical sleeve gastroplasty Long-term quality of life after vertical sleeve gastroplasty We conducted a historical cohort study including patients with morbid obesity the in the Unified Health System (SUS), registered in the database of the General University Hospital, University of Cuiabá. All patients underwent vertical sleeve gastroplasty and were followed for at least one year after the operation. The study variables were: quality of life, weight loss, improvement of hypertension and diabetes, and mortality. Results Results ResultsResults Results: The sample comprised 41 patients, 13 (31.7%) men and 28 (61.3%) women, mean age was 37 years, the average weight was 136.4 kg and mean BMI 50.3 kg/m 2 ; mean follow-up was 19.1 months (12-32). There was a significant reduction in weight (96.7 kg, p < 0.001) and BMI (35.835 kg/m 2 , p < 0.001). The rate of blood pressure decreased from 56% to 31.7%, and diabetes from 14.6% to 4.8% (p < 0.001). Quality of life improved in 92.5% of patients. ConclusionConclusion Conclusion Conclusion Conclusion: There was an improvement in the quality of life in the majority of patients, achieved by means of weight loss and clinical improvement of diabetes and hypertension.

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“…Given the effectiveness of LSG in super-super-obese and super-obese patients, Langer et al [40] reported the results of LSG in morbidly obese patients. A total of 23 patients (8 super-obese and 15 with a BMI < 50 kg/m ) were included in the prospective study.…”

Section: Weight-loss Outcomesmentioning

confidence: 99%

Updated Review of Sleeve Gastrectomy

Trelles¹,

Gautier²

2008

TOGASJ

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There is a bariatric explosion worldwide to deal with the rising prevalence of morbid obesity. In 1988, Hess and Hess first added the sleeve gastrectomy (SG) and the duodenal switch (DS) as a modification to the biliopancreatic diversion (BPD) to improve clinical outcomes. But the increased morbidity and mortality observed in super-super-obese patients (BMI > 60 kg/m ) who underwent BPD with DS (BPD-DS) made Gagner and co-workers propose SG as a bridge to gastric bypass or BPD-DS to reduce complications and mortality. The excellent short-term weight-loss outcomes after SG have increased the enthusiasm among surgeons to use it as a definitive treatment for morbidly obese and super-obese patients (BMI > 50 kg/m ). Neurohormonal and gastric emptying changes may account for its superiority over other restrictive procedures. Recent reports on mid-term weight-loss outcomes make this procedure a viable option for bariatric surgeons; nonetheless, long-term studies are still required.

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Does Gastric Dilatation Limit the Success of Sleeve Gastrectomy as a Sole Operation for Morbid Obesity?

Cited by 208 publications

References 42 publications

Hematological, Biochemical, and Immunological Laboratory and Histomorphological Effects of Sleeve Gastrectomy on Female Rats

Hematological, Biochemical, and Immunological Laboratory and Histomorphological Effects of Sleeve Gastrectomy on Female Rats

Avaliação da qualidade de vida tardia após gastroplastia vertical

Updated Review of Sleeve Gastrectomy

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