“…Indeed it may be the desired outcome. Chestnut et al [2] in a randomized controlled trial in fetal lambs showed a significant effect of a rapid packed red cell transfusion on central venous pressure, mean arterial blood pressure and heart rate and these effects were the same whether or not the lambs had received frusemide. The rate of the transfusion was 2 ml/kg per minute, mean total transfusion time of 10 min, that is 40 times the rate used by Rascher et al [9] who found no haemodynamic effects.…”