volume 27, issue 1, P99-114 2013
DOI: 10.1016/j.idc.2012.11.005
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Thomas M. File, Thomas J. Marrie

Abstract: The present controversy regarding the need to cover atypical pathogens in the empiric therapy of community-acquired pneumonia is related to several issues, including the relevance of terminology, imprecise diagnostic methods, and perceived contradictory results of published evidence. Studies evaluating the time to clinical recovery and the use of earlier endpoints for evaluation suggest that appropriate therapy provides a benefit if an atypical pathogen is a pathogen. Because recent surveillance studies sugges…

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