1972
DOI: 10.1001/archderm.106.5.767b
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Does cellophane tape stripping remove the horny layer?

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Cited by 6 publications
(3 citation statements)
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“…The first studies using this technique were done in the early 1970s [112][113][114]. Flux may be increased as a result of a reduced SC thickness, or a penetrant may have direct access to the viable epidermis on complete elimination of the SC.…”
Section: Tape Strippingmentioning
confidence: 99%
“…The first studies using this technique were done in the early 1970s [112][113][114]. Flux may be increased as a result of a reduced SC thickness, or a penetrant may have direct access to the viable epidermis on complete elimination of the SC.…”
Section: Tape Strippingmentioning
confidence: 99%
“…Though the skin barrier properties were damaged by the strippings in the current study and no stratum corneum was visible in the histological studies, others have shown that the stratum corneum cannot be totally removed by stripping. Up to a third of the layer will remain attached, as islets, to the epidermal surface [7]. Rougier et al [8] removed the stratum corneum of hairless rats by 6 strippings.…”
Section: Discussionmentioning
confidence: 99%
“…Μετά την εφαρμογή των παραπάνω ουσιών στην επι φάνεια του δέρματος και αφού περάσει ορισμένος χρόνος, αφαιρεί ται η κεράτινη με σελοτέιπ ή ειδική κόλλα και προσδιορίζεται το ποσόν της ουσίας που έχει διαχυθεί σ'αυτήν. Βέβαια με τη μέθο δο αυτή δεν αφαιρείται ολόκληρη η κεράτινη στιβάδα αλλά μόνο τα 2/3 της και μετά την αφαίρεση αυτή παραμένουν νησίδια κεράτινης πάνω στην υπόλοιπη επιδερμίδα που δεν μπορούν να αφαιρεθούν μ'au τόν τον τρόπο (Holyo-Tomoka and Kligman 1972).…”
Section: In Vivo μεθοδοιunclassified