Do patients with non‐radiographic axial spondylarthritis differ from patients with ankylosing spondylitis?

Abstract

Conclusion.Patients with nr-axSpA were characterized by the low proportion of male patients and the low burden of inflammation compared to patients with AS. While both groups did not differ regarding health status, disease activity, and physical function, they did differ in signs of inflammation; all were higher in patients with AS. Since many patients with nr-axSpA had not developed structural changes after years of symptoms, we propose that those patients should not be regarded as having preradiographic AS but rather as having nr-axSpA.

Prevalence and factors associated with disturbed sleep in patients with ankylosing spondylitis and non-radiographic axial spondyloarthritis: a systematic review

“…Regular exercise is already emphasised as an important aspect of the long-term management of AS [ 1 ] and has been shown to have an analgesic effect [ 65 ] which may help AS patients cope with pain. Masiero et al [ 66 ] found that exercise, in combination with an educational-behavioural program and anti-TNF therapy, had a greater effect on symptoms of disease activity in AS patients than either intervention used alone.…”

“…Patients with ankylosing spondylitis (AS) and non-radiographic axial spondyloarthritis (nraxSpA) share similar burdens of illness in terms of pain, functional impairment, quality of life (QoL) and the need for effective treatment [ 1,2 ]. Pain and stiffness in the axial spine impact functional ability and QoL [ 3,4 ] and patients have associated these symptoms with poor sleep [ 5,6 ].…”

The Evolution of Axial Spondyloarthritis During 12-Month Follow-Up Study of a Corsar Cohort

“…Описываемые в литературе различия между нр-аксСпА и АС, такие как более высокая активность [9][10][11], худшие функциональные возможности [12] и большая до-ля мужчин среди больных АС [9,10], на основании пред-варительного анализа данных когорты КоРСаР подтвер-дить не удалось, хотя мы ожидали, что наши результаты подтвердят отмеченные выше различия между двумя кли-ническими вариантами аксСпА. И этому есть логичное объяснение.…”

Comparative Evaluation of Patients With Ankylosing Spondylitis and Non-Radiographic Axial Spondyloarthritis

“…По данным U. Kiltz и соавт [12], в группе пациентов с дорентгенологической стадией было больше женщин, а уровень СРБ и функциональная активность значительно выше у пациентов с установленным диагнозом АС, хотя О р и г и н а л ь н ы е и с с л е д о в а н и я Примечание. *-р<0,01.…”