volume 99, issue 3, P438-444 1997
DOI: 10.1542/peds.99.3.438
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S. G. Rothrock, M. B. Harper, S. M Green, M. C. Clark, R. Bachur, D. P. McIlmail, P. A. Giordano, J. L. Falk

Abstract: Although oral antibiotics modestly decreased the risk of serious bacterial infections in children with S pneumoniae occult bacteremia, there was insufficient evidence to conclude that oral antibiotics prevent meningitis. Published recommendations that oral antibiotics be administered to prevent serious bacterial infections in children with possible S pneumoniae occult bacteremia should be reevaluated in light of the lower risk of sequelae from S pneumoniae occult bacteremia and newer data concerning side effec…

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