Do 6-Month Motor Skills Have Cascading Effects on 12-Month Motor and Cognitive Development in Extremely Preterm and Full-Term Infants?

Zuccarini, Mariagrazia; Guarini, Annalisa; Savini, Silvia; Faldella, Giacomo; Sansavini, Alessandra

doi:10.3389/fpsyg.2020.01297

Cited by 10 publications

(10 citation statements)

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“…Consistent associations of microbiota b-diversity with infant gut microbiota were observed for FM subscale in our study. FM abilities refer to the control of small muscles that is highly related to cognitive functions that process visual information [ 39 ]. Despite this connection, examination of Bayley ® -III scales showed no significant associations of cognitive and language subscales with gut microbiota in our cohort.…”

Section: Discussionmentioning

confidence: 99%

Infant Gut Microbiota Associated with Fine Motor Skills

et al. 2021

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BACKGROUND: During early life, dynamic gut colonization and brain development co-occur with potential cross-talk mechanisms affecting behaviour. METHODS: We used 16S rRNA gene sequencing to examine the associations between gut microbiota and neurodevelopmental outcomes assessed by the Bayley Scales of Infant Development III in 71 full-term healthy infants at 18 months of age. We hypothesized that children would differ in gut microbial diversity, enterotypes obtained by Dirichlet multinomial mixture analysis and specific taxa based on their behavioural characteristics. RESULTS: In children dichotomized by behavioural trait performance in above- and below-median groups, weighted Unifrac b-diversity exhibited significant differences in fine motor (FM) activity. Dirichlet multinomial mixture modelling identified two enterotypes strongly associated with FM outcomes. When controlling for maternal pre-gestational BMI and breastfeeding for up to 3 months, the examination of signature taxa in FM groups showed that Turicibacter and Parabacteroides were highly abundant in the below-median FM group, while Collinsella, Coprococcus, Enterococcus, Fusobacterium, Holdemanella, Propionibacterium, Roseburia, Veillonella, an unassigned genus within Veillonellaceae and, interestingly, probiotic Bifidobacterium and Lactobacillus were more abundant in the above-median FM group. CONCLUSIONS: Our results suggest an association between enterotypes and specific genera with FM activity and may represent an opportunity for probiotic interventions relevant to treatment for motor disorders.

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Section: Discussionmentioning

confidence: 99%

Infant Gut Microbiota Associated with Fine Motor Skills

et al. 2021

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“…The cascading effects of early motor development on other developmental domains in preterm children have been highlighted in several studies (Zuccarini et al, 2020). Developmental changes in one domain can have cascading effects on others, even seemingly unrelated ones-they can be direct or indirect as well as multidirectional (Iverson, 2021(Iverson, ).…”

Section: Discussionmentioning

confidence: 99%

“…Furthermore, studies that used standardized assessment tools reported similar results at different ages. Gross motor skills assessed at 6 months by Griffiths Mental Developmental Scales were associated with cognitive skills at 12 months with the same instrument ( Zuccarini et al, 2020 ). The Prechtl General Movement Assessment (GMA) also was associated with cognitive outcomes assessed with different tools from 2 to 11 years old ( Einspieler et al, 2016 ).…”

Section: Discussionmentioning

confidence: 99%

“…Children born preterm have higher neurodevelopment impairments rates than their term peers (Beauregard et al, 2018;Sanchez et al, 2019;Valentini et al, 2019;Zuccarini et al, 2020;Sandoval et al, 2021). They have a high risk for delays across multiple domains like motor, cognitive, language, or social development, even without major cerebral damage (Aylward, 2005).…”

Section: Introductionmentioning

confidence: 99%

“…The early identification of impairments allows intervention as early as possible, preferably before school age, to prevent academic difficulties and failures. However, although motor differences can be noticeable at 2-months of age or even earlier for preterm children ( Aylward, 2005 ; Sampaio et al, 2015 ), cognitive and language deficits do not manifest until older ages–most at a pre-school or older age ( Sanchez et al, 2019 ; Zuccarini et al, 2020 ). However, even before cognitive and language impairments are noticeable, these children could benefit from early intervention and perhaps minimize the difficulties in the child’s life and academic performance.…”

Section: Introductionmentioning

confidence: 99%

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Motor development in the first year of life predicts impairments in cognition and language at 3 years old in a Brazilian preterm cohort of low-income families

Panceri

Silveira²,

Procianoy³

et al. 2022

Front. Neurosci.

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PurposeEarly identification of impairments is crucial to providing better care for preterm children, especially those from low-income families. The early motor assessment is the first step in monitoring their neurodevelopment. This study investigates if motor development in the first year of life predicts impairments in cognition and language at 3-year-old in a Brazilian preterm cohort.Materials and methodsData were collected in a follow-up clinic for high-risk infants. The Bayley Scales were used to assess children at 4, 8, 12, and 36 months of age, considering composite scores. Cognitive and language impairments were considered if scores were ≤85. Children (N = 70) were assessed at 4 and 36 months, 79 were assessed at 8 and 36 months, and 80 were assessed at 12 and 36 months. Logistic regressions were used to analyze the predictability of cognitive and language impairments, and receiver-operating characteristics (ROC) curves were used to analyze the sensibility and specificity of motor assessment and cognitive and language impairments.ResultsPoor motor scores at 8 and 12 months increased the chances of cognitive and language impairment at 3-year-old. The chance of cognitive impairment at 3-year-old increases by 6–7% for each point that the motor composite score decreases, and the chance of language impairment at 3-year-old increases by 4–5% for each point that the motor composite score decreases. No-significant results were found at 4-months. Adequate sensibility and specificity were found for language impairments considering 12 months scores and for cognitive impairments as soon as 8 months scores.ConclusionMonitoring preterm motor development in the first year of life helps to identify preterm children at risk for impairment in other developmental domains. Since preterm children from low-income families tend to demonstrate poorer neurodevelopment outcomes, these children need early assessment and referral to intervention to prevent school failures and support from public policies.

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Relationship Between Prone Skills and Motor‐Based Problem‐Solving Abilities in Full‐Term and Preterm Infants During the First 6 Months of Life

Inamdar,

Tripathi,

Molinini

et al. 2024

Developmental Psychobiology

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Motor experiences shape cognitive development in infancy, with the prone position being one such crucial motor experience in the first 6 months of life. Although the motor benefits of the prone position are well‐documented, its influence on early cognitive abilities remains insufficiently explored. This study quantified the relationship between prone motor skills and motor‐based problem‐solving abilities in 48 full‐term and preterm infants aged 3–6 months. Prone skills were assessed using the Alberta Infant Motor Scale's prone domain. The Assessment of Problem‐Solving in Play was utilized to measure motor‐based problem‐solving by observing how motor actions were used to solve toys. Advanced prone motor skills were correlated with an increase in sophisticated exploration skills and a concurrent decline in lower order exploration skills in all infants, with correlations being stronger in preterm infants. Notably, a 1‐point increase in prone skills was associated with a 1.3‐point increase in total motor‐based problem‐solving abilities in all infants. Our findings provide preliminary evidence for the contribution of prone play to cognitive development in infants, prompting considerations for assessment and intervention strategies. Further research is needed to ascertain if the delayed acquisition of prone motor skills is indicative of poor early problem‐solving abilities in preterm infants.

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Do 6-Month Motor Skills Have Cascading Effects on 12-Month Motor and Cognitive Development in Extremely Preterm and Full-Term Infants?

Cited by 10 publications

References 50 publications

Infant Gut Microbiota Associated with Fine Motor Skills

Infant Gut Microbiota Associated with Fine Motor Skills

Motor development in the first year of life predicts impairments in cognition and language at 3 years old in a Brazilian preterm cohort of low-income families

Relationship Between Prone Skills and Motor‐Based Problem‐Solving Abilities in Full‐Term and Preterm Infants During the First 6 Months of Life

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