DNA-mediated regioselective encoding of colloids for programmable self-assembly

Abstract

This review provides a comprehensive overview of the latest advances in DNA-mediated regioselective encoding of colloids, emphasizing the critical role of regioselective DNA recognition in the assembly of colloidal structures and their applications.

DNA nanostructures for exploring cell–cell communication

“…Waston–Crick properties of complementary base pairing afford DNA with two unparalleled advantages, (1) unique recognition capabilities and (2) programmable self-assembly. 20 Also, DNA exhibits the following advantages: (3) functional nucleic acids, such as DNAzymes and aptamers, with unique structures as well as targeting capabilities, 21 and (4) good biocompatibility and biodegradability. 22 Based on these characteristics, single-stranded DNA, double-stranded DNA, and triple-stranded DNA can be selected to build flexible designs according to the requirements of the scheme.…”

Importance of DNA nanotechnology for DNA methyltransferases in biosensing assays

“…Critically, in recent decades, various breakthroughs have been made in DNA structural nanotechnology, employing the properties of nucleic acids, such as the double helix form, Watson–Crick base pairing interactions, and programmable sequences, to build specific nanostructures and nanodevices. 61–63…”

Construction and bioanalytical applications of poly-adenine-mediated gold nanoparticle-based spherical nucleic acids

“…14 Therefore, AuNP-based SNAs have attracted much attention and been applied in the fields of biosensors, 15–19 cell imaging, 20–22 therapy, 23,24 and materials science. 25,26 Typically, the DNA–AuNPs conjugates of SNAs are established by self-assembly of thiolated oligonucleotides at the surface of AuNPs based on strong Au–S chemistry. 27 In fact, the covalent surface chemistry ( i.e.…”