2012
DOI: 10.1016/j.jep.2012.01.017
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Diuretic activity of some Smilax canariensis fractions

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Cited by 24 publications
(17 citation statements)
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“…A calibrated pH meter (Model: WTW-Series pH-720) was used to estimate pH of the fresh urine samples [12,16].…”
Section: Determination Of Ph Of Urinementioning
confidence: 99%
See 1 more Smart Citation
“…A calibrated pH meter (Model: WTW-Series pH-720) was used to estimate pH of the fresh urine samples [12,16].…”
Section: Determination Of Ph Of Urinementioning
confidence: 99%
“…The following equations were used to compute these parameters [15,16]. where UVt = mean urine volume of test group, UVc = mean urine volume of control group, UVr = mean urine volume of reference group, CUEt = concentration of electrolytes in urine of test group, CUEc = concentration of electrolytes in urine of control group, UNa + = concentration of Na + in urine of a group, and UK + = concentration of K + in urine of a group.…”
Section: Assessment Of Acute Toxicitymentioning
confidence: 99%
“…For example, the presence of polar organic compounds as flavonoid glycosides and saponosids in plants can produce diuresis because they are more likely to have contact with renal tissues (Lahlou et al, 2007;Adam et al, 2009;Amuthan et al, 2012;Meléndez-Camargo et al, 2014). Natural compounds in medicinal plants might stimulate the regional blood flow and/or promote an initial vasodilatation as do the osmotic diuretics and xanthenes (Osswald and Schnermann, 2011;Saleem et al, 2015), but might also produce inhibition of renal tubular reabsorption of water and anions (Abdala et al, 2012;Gasparotto et al, 2011); the result in these cases is diuresis. In addition, the electrolytes present in plants can induce a diuretic activity (Adam et al, 2009).…”
Section: Discussionmentioning
confidence: 99%
“…Group 4 (Test) -received aqueous extract of Centella asiatica (500mg/kg, p.o.). [14,15,16,17] Before the oral administration of test drugs, the animals were dosed/hydrated with 25 ml/kg body weight of normal saline (0.9% …”
Section: Drugsmentioning
confidence: 99%