volume 26, issue 4, P755-766 2011
DOI: 10.3233/jad-2011-110002
View full text
Retracted 2016-11-01
|
|
Share
Kevin H. Chen, Edmund A. Reese, Hyung-Wook Kim, Stanley I. Rapoport, Jagadeesh S. Rao

Abstract: Alzheimer disease (AD) is a neurodegenerative disorder characterized by memory loss and behavioral and psychological symptoms of dementia. An imbalance of different neurotransmitters – glutamate, acetylcholine, dopamine, and serotonin - has been proposed as the neurobiological basis of behavioral symptoms in AD. The molecular changes associated with neurotransmission imbalance in AD are not clear. We hypothesized that altered reuptake of neurotransmitters by vesicular glutamate transporters (VGLUTs), excitato…

expand abstract
editorial notices