Disturbances in Sleep Mechanism: A Clinicopathologic Study

The physiology of motivation.

“…Decortication in dogs, for example, results in an inability to postpone sleep and remain awake for very long, or, as Kleitman puts it, a return to polyphasic sleep and waking rhythms (38, 39). Studies of humans, moreover, show that even restricted lesions of the cortex or thalamus alone can result in an inability to stay awake normally (25, 26). But no inhibitory effects of the cortex in sleep have yet been uncovered.…”

The physiology of motivation.

“…Decortication in dogs, for example, results in an inability to postpone sleep and remain awake for very long, or, as Kleitman puts it, a return to polyphasic sleep and waking rhythms (38, 39). Studies of humans, moreover, show that even restricted lesions of the cortex or thalamus alone can result in an inability to stay awake normally (25, 26). But no inhibitory effects of the cortex in sleep have yet been uncovered.…”

The physiology of motivation.

“…Decortication in dogs, for example, results in an inability to postpone sleep and remain awake for very long, or, as Kleitman puts it, a return to polyphasic sleep and waking rhythms (38, 39). Studies of humans, moreover, show that even restricted lesions of the cortex or thalamus alone can result in an inability to stay awake normally (25, 26). But no inhibitory effects of the cortex in sleep have yet been uncovered.…”

The physiology of motivation.

“…Decortication in dogs, for example, results in an inability to postpone sleep and remain awake for very long, or, as Kleitman puts it, a return to polyphasic sleep and waking rhythms (38, 39). Studies of humans, moreover, show that even restricted lesions of the cortex or thalamus alone can result in an inability to stay awake normally (25, 26). But no inhibitory effects of the cortex in sleep have yet been uncovered.…”