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Cited by 26 publications
(22 citation statements)
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“…Obesity is consistently associated with a set of metabolic diseases, including hypertension, atherosclerosis, dyslipidaemia, and type 2 DM, which commonly occur with MS 1,2,14,27,28. Furthermore, MS is characterized by hyperinsulinaemia and different IR intensities, which explains the relationship between various abnormalities and obesity 2,27.…”
Section: Discussionmentioning
confidence: 99%
“…Obesity is consistently associated with a set of metabolic diseases, including hypertension, atherosclerosis, dyslipidaemia, and type 2 DM, which commonly occur with MS 1,2,14,27,28. Furthermore, MS is characterized by hyperinsulinaemia and different IR intensities, which explains the relationship between various abnormalities and obesity 2,27.…”
Section: Discussionmentioning
confidence: 99%
“…Furthermore, the HOMA-IR mean values for DM1 did not differ from those of the DM2 group (Table 1), and did not show correlation with BChE activities in the DM1 group using logistic regression analyses. The HOMA-IR has been positively correlated to BMI (39).…”
Section: Butyrylcholinesterase and Diabetes Mellitusmentioning
confidence: 94%
“…Laboratory evaluation included lipid profile (total cholesterol, triglycerides, lowdensity lipoprotein, and high-density lipoprotein), FFAs, glucose, insulin, high-sensitivity C-reactive protein (CRP), and liver enzyme markers (alanine aminotransferase, aspartate aminotransferase, and gamma glutamyl transferase). The index Homeostasis Model Assessment-Insulin Resistance [HOMA1-IR) = fasting insulin (mU/L) 9 fasting glucose (mmol/L)/22.5] was calculated and classified according to body mass index (BMI) [24,25]. Blood glucose and lipid profiles were assessed using the enzymatic colorimetric method and the kinetic test for liver enzymes, and high-sensitivity CRP was analyzed using the immunoturbidimetric test; all these parameters were determined with the use of Bioclin Kits (Quibasa Basic Chemical Ltda, Belo Horizonte, Brazil) equipped with a BS-200 Chemistry Analyzer (Mindray Medical International, Shenzhen, China).…”
Section: Safety Assessmentmentioning
confidence: 99%