2011
DOI: 10.1097/nmd.0b013e3182043b60
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Distinctive Clinical Characteristics and Suicidal Tendencies of Patients With Anxious Depression

Abstract: This study evaluated clinical characteristics and suicidality of patients with anxious depression in a large cohort of samples. Data were collected from 1003 patients who were depressed. A total of 461 patients were diagnosed with anxious depression and 542 were diagnosed with nonanxious depression. After adjusting for the severity of depression, those in the anxious depression group had significantly younger onset age, had been suffering from depression for a longer period, were more likely to experience a re… Show more

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Cited by 77 publications
(49 citation statements)
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“…These findings agree with Zisook et al (2009) who found that depression severity, concurrent substance abuse and melancholia were associated with TESI in a report from the STAR*D trial. Likewise, other studies have pointed at depression severity, medical, and psychiatric comorbidity (including anxiety) as predictors of suicidal ideation independent of treatment (Alexopoulos et al ., 2009; Bogers et al ., 2013; Shah et al ., 2000; Lenze et al ., 2000; Seo et al ., 2011)…”
Section: Discussionmentioning
confidence: 99%
“…These findings agree with Zisook et al (2009) who found that depression severity, concurrent substance abuse and melancholia were associated with TESI in a report from the STAR*D trial. Likewise, other studies have pointed at depression severity, medical, and psychiatric comorbidity (including anxiety) as predictors of suicidal ideation independent of treatment (Alexopoulos et al ., 2009; Bogers et al ., 2013; Shah et al ., 2000; Lenze et al ., 2000; Seo et al ., 2011)…”
Section: Discussionmentioning
confidence: 99%
“…Their comorbidity is particularly striking in rates of current co-occurrence: 45–67% of individuals diagnosed with a unipolar depressive disorder meet criteria for at least one concurrent anxiety disorder, and 30–63% of individuals diagnosed with an anxiety disorder meet criteria for concurrent unipolar depression (Brown et al, 2001; Fava et al, 2000; Lamers et al, 2011). This form of co-occurrence is associated with a more severe and protracted clinical course, greater disability, and higher risk for suicide than is either category of disorder alone (Ballenger et al, 2001; Bruce et al, 2005; Fava et al, 2006; Kessler et al, 1999; Lamers et al, 2011; Roy-Byrne et al, 2000; Seo et al, 2011; van Balkom et al, 2008). It is perhaps not surprising, therefore, that persons with co-occurring depression and anxiety are more likely to utilize mental health care services than are their counterparts who have either condition alone (Kessler et al, 2015; McLaughlin et al, 2006).…”
Section: Introductionmentioning
confidence: 99%
“…Depression severity (Roy, 1993), co-morbid personality disorder (Corbitt et al 1996; Soloff et al 2000), anxiety disorder (Stein et al 2001; Sareen et al 2005; Bolton et al 2008 b ), panic attacks (Katz et al 2011) and alcohol-use disorders (Bulik et al 1990; Claassen et al 2007) have all been associated with an elevated risk of suicide attempt in depressed patients. Another study found that anxious depression patients were characterized by significantly higher scores on the Scale for Suicide Ideation (Seo et al 2011). …”
Section: Introductionmentioning
confidence: 99%