Dissociation of boldness and disinhibition psychopathic traits in ERN modulation

Pasion, Rita; Cruz, Ana Rita; Barbosa, Fernando

doi:10.1016/j.paid.2016.02.017

Cited by 26 publications

(20 citation statements)

References 25 publications

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“…Studies that have specifically assessed antagonistic external izing tendencies along with broad externalizing have shown reduced P3 and ERN in relation to the latter, but not to antag onismspecific variance 221,222 . By contrast, high antagonistic externalizing is reliably associated with reduced brain reactivity to fearful face stimuli.…”

Section: Neurophysiological Indicatorsmentioning

confidence: 99%

Validity and utility of Hierarchical Taxonomy of Psychopathology (HiTOP): II. Externalizing superspectrum

et al. 2021

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The Hierarchical Taxonomy of Psychopathology (HiTOP) is an empirical effort to address limitations of traditional mental disorder diagnoses. These include arbitrary boundaries between disorder and normality, disorder co‐occurrence in the modal case, heterogeneity of presentation within disorders, and instability of diagnosis within patients. This paper reviews the evidence on the validity and utility of the disinhibited externalizing and antagonistic externalizing spectra of HiTOP, which together constitute a broad externalizing superspectrum. These spectra are composed of elements subsumed within a variety of mental disorders described in recent DSM nosologies, including most notably substance use disorders and “Cluster B” personality disorders. The externalizing superspectrum ranges from normative levels of impulse control and self‐assertion, to maladaptive disinhibition and antagonism, to extensive polysubstance involvement and personality psychopathology. A rich literature supports the validity of the externalizing superspectrum, and the disinhibited and antagonistic spectra. This evidence encompasses common genetic influences, environmental risk factors, childhood antecedents, cognitive abnormalities, neural alterations, and treatment response. The structure of these validators mirrors the structure of the phenotypic externalizing superspectrum, with some correlates more specific to disinhibited or antagonistic spectra, and others relevant to the entire externalizing superspectrum, underlining the hierarchical structure of the domain. Compared with traditional diagnostic categories, the externalizing superspectrum conceptualization shows improved utility, reliability, explanatory capacity, and clinical applicability. The externalizing superspectrum is one aspect of the general approach to psychopathology offered by HiTOP and can make diagnostic classification more useful in both research and the clinic.

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Section: Neurophysiological Indicatorsmentioning

confidence: 99%

Validity and utility of Hierarchical Taxonomy of Psychopathology (HiTOP): II. Externalizing superspectrum

et al. 2021

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“…Although more extensive, research on error processing in psychopathy has yielded conflicting results as well. Studies of incarcerated offenders assessed using the Psychopathy Checklist-Revised (PCL-R; Hare, 2003) or its derivatives suggest a general pattern of intact ERN amplitude during standard (cognitive) speeded response tasks (e.g., Brazil et al, 2009;Maurer, Steele, Cope, et al, 2016;Maurer, Steele, Edwards, et al, 2016;Munro et al, 2007b;, whereas studies with community samples employing self-report assessment instruments -such as the Psychopathic Personality Inventory (PPI; Lilienfeld & Widows, 2005) or the Triarchic Psychopathy Measure (TriPM; Patrick, 2010) -have reported diminished ERN amplitude in relation to higher scores on disinhibition and impulsive-antisocial traits in different tasks (Heritage & Benning, 2013;Pasion, Cruz, & Barbosa, 2016). Bresin, Finy, Sprague, and Verona (2014) likewise reported evidence for reduced ERN in relation to impulsiveantisocial features in a sample assessed for psychopathy using the screening version of Hare's PCL-R.…”

Section: Performance Monitoring Deficits In Psychopathy and Externalizing Psychopathologymentioning

confidence: 99%

Electrocortical measures of performance monitoring from go/no‐go and flanker tasks: Differential relations with trait dimensions of the triarchic model of psychopathy

et al. 2020

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This study examined associations of performance‐monitoring event‐related potentials (ERPs) from go/no‐go and flanker tasks with one another, and with psychopathy‐related traits of disinhibition, meanness, and boldness. A task‐dependent relationship was evident between the error‐related negativity (ERN) and trait disinhibition, with high‐disinhibited participants showing reduced no‐go ERN but not flanker ERN. Disinhibition was also inversely related to variants of the P3 and the error positivity (Pe) from these two tasks. A factor analysis of the ERPs revealed two distinct factors, one reflecting shared variance among the P3 and Pe measures from the two tasks, and the other covariance among the N2 and ERN measures. Scores on the P3/Pe factor, but not the N2/ERN factor, were inversely related to disinhibition, and accounted for associations of this trait with variants of the P3 and Pe across tasks. The implication is that high trait disinhibition relates mainly to reductions in brain responses associated with later elaborative stages in the processing of motivationally significant events across different tasks. Importantly, no‐go ERN predicted disinhibition scores beyond N2/ERN factor scores, indicating that high disinhibition is not generally related to diminished early preresponse conflict and error processing, but rather to processing impairments in conditions calling for inhibition of prepotent response tendencies.

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“…Of high importance, it is very common not to find significant differences in behavioral parameters while these differences may be detected at the neurobiological level (e.g. Gonz alez-Villar et al, 2017;Langer et al, 2013;Pasion et al, 2016a).…”

Section: Resultsmentioning

confidence: 99%

Fostering advances to neuropsychological assessment based on the Research Domain Criteria: The bridge between cognitive functioning and physiology

Geraldo

Azeredo

Pasion

et al. 2018

The Clinical Neuropsychologist

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Objectives: The current review aimed to explore the advances in neuropsychological assessment in light of a recent research framework designed to improve our knowledge on mental health the Research Domain Criteria (RDoC). Methods: RDoC proposals on neuropsychological tests were reviewed across the RDoC cognitive systems domain. The focus is on the physiological unit of analysis and the potential applications are illustrated given the functional relevance of RDoC constructs to psychopathological and neurological conditions. Results: The advances in neuropsychology anchored in RDoC are not observable in terms of innovative paradigms, but rather in the neurobiological correlates that may be obtained from the classical neuropsychological tasks. The behavior unit of analysis may be integrated with physiological outcomes while mapping distinct cognitive constructs simultaneously. Conclusions: Under the aegis of RDoC, the integration of multiple levels of analysis allows to obtain a more detailed and complete neuropsychological characterization with high potential to be translated into better intervention strategies.

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Dissociation of boldness and disinhibition psychopathic traits in ERN modulation

Cited by 26 publications

References 25 publications

Validity and utility of Hierarchical Taxonomy of Psychopathology (HiTOP): II. Externalizing superspectrum

Validity and utility of Hierarchical Taxonomy of Psychopathology (HiTOP): II. Externalizing superspectrum

Electrocortical measures of performance monitoring from go/no‐go and flanker tasks: Differential relations with trait dimensions of the triarchic model of psychopathy

Fostering advances to neuropsychological assessment based on the Research Domain Criteria: The bridge between cognitive functioning and physiology

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