Dissemination of Spirochaeta Pallida in Experimental Syphilis

Eberson, Frederick

doi:10.1001/archderm.1921.02350140003001

Arch Derm Syphilol

1921

DOI: 10.1001/archderm.1921.02350140003001

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Dissemination of Spirochaeta Pallida in Experimental Syphilis

Frederick Eberson¹

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1921

1937

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Cited by 12 publications

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“…Treatment consists of a careful coordination of the following factors: (1) rest in bed, (2) Signs of Vitamin A Deficiency.-The signs of gross deficiency of vitamin A in human beings most frequently recog¬ nized are xerophthalmia and acquired night-blindness, which are not uncommonly associated in the same individual. Such cases are met with in our own country, and it is of importance that this fact should be recognized because they respond very quickly to appropriate treatment in their early stages and can be completely cured.…”

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confidence: 99%

Generalized Angiomatosis (Telangiectasia)

Madden¹

1934

JAMA

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mentioning

confidence: 99%

Generalized Angiomatosis (Telangiectasia)

Madden¹

1934

JAMA

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Xxi.—a Biologic Study of Latency in Syphilis

Engman¹,

Eberson²

1921

Arch Derm Syphilol

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To give a clear idea of the meaning of latency, we must point to a few biologic facts in relation to the invasive stage of syphilis. After a given infection, when the virus is deposited on an abraded surface, the organisms begin to proliferate and are wafted quickly into the general circulation, as has been actually demonstrated by Brown and Pearce 1 and one of us.2 The organisms continue to increase at the site of the lesion and probably within the body until the period of multiple systemic localization occurs. When the spirochetes are planted in the tissues and organs of the body, colonies are formed and through their growth and life cycle induce certain biochemical changes which may be exhibited in all organs; and, no matter where located, seem to stimulate the same cellular reaction. They arrive by way of the blood stream in these various organs and especially in the skin where they continue proliferation. Their presence induces at these points of colonization the formation of lymphoid cells, plasma cells and new connective-tissue cells and sometimes giant cells (a papule), but the organism exerts little attraction for the polymorphonuclear leukocytes. The new-formed cells have not the power of reorganization and have a tendency toward résorption and disin-Studies, reports and observations from the

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Xxiii.—immunity Studies in Experimental Syphilis

Eberson¹

1921

Arch Derm Syphilol

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Dissemination of Spirochaeta Pallida in Experimental Syphilis

Cited by 12 publications

References 2 publications

Generalized Angiomatosis (Telangiectasia)

Generalized Angiomatosis (Telangiectasia)

Xxi.—a Biologic Study of Latency in Syphilis

Xxiii.—immunity Studies in Experimental Syphilis

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