Disseminated verruciform xanthoma

Sopena, J.; Gamo, R. Scott; Iglesias, L.; Rodríguez-Peralto, José L.

doi:10.1111/j.1365-2133.2004.06164.x

Cited by 23 publications

(20 citation statements)

References 10 publications

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“…VX manifests as an asymptomatic solitary, slow-growing plaque or nodule with a papillary, granular or verrucous surface and sharply delineated margins that may appear pink, red, yellow, or white in color [1]. The occurrence of multiple or disseminated VX is extremely rare [24,32,33]. Approximately 75% of all oral VX lesions occur on the masticatory mucosa of the palate, gingiva or the alveolar ridge [1].…”

Section: Discussionmentioning

confidence: 98%

Oral Verruciform Xanthoma Associated with Chronic Graft-Versus- Host Disease: A Report of Five Cases and a Review of the Literature

Farahani

Treister

Khan

et al. 2011

Head and Neck Pathol

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Verruciform xanthoma (VX) is an uncommon benign inflammatory mucocutaneous condition that chiefly occurs in the oral cavity. It is often associated with pre-existing epithelial and/or inflammatory disorder and is characterized histopathologically by papillary epithelial hyperplasia and the presence of foamy macrophages in connective tissue papillae. We report of a series of five cases with VX who concurrently had chronic oral graft-versus-host disease following hematopoietic stem cell transplantation.

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Section: Discussionmentioning

confidence: 98%

Oral Verruciform Xanthoma Associated with Chronic Graft-Versus- Host Disease: A Report of Five Cases and a Review of the Literature

Farahani

Treister

Khan

et al. 2011

Head and Neck Pathol

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“…In a series of 15 cases, Yu et al 8 did not find any verruciform xanthoma in the palate but found one lesion in the palatine gingiva. Sopena et al 5 found small lesions in the palate of a patient with many verruciform xanthomas in the skin.…”

Section: Discussionmentioning

confidence: 99%

“…Up to 2001, only 282 cases had been reported4. Since 2001, the following reports written in English were found in PubMed: a series with 15 new cases described by Yu et al 8 ; another two cases reported by Sah et al 7 ; and 11 isolated case reports, totaling 29 new cases including the present case 5,[11][12][15][16][17][18][19][20][21][22] . Among all cited studies, only five verruciform xanthomas were described, in addition to the present case 12,14 .…”

Section: Discussionmentioning

confidence: 99%

“…The lesion is usually solitary and asymptomatic, and can have been present from a few weeks to years 4 . Sopena et al 5 described a case of disseminated verruciform xanthoma involving the hands, feet, genital region, ears, and palate. From the clinical point of view, verruciform xanthoma is characterized by a well delimited rough or papillary elevation and may be depressed or ulcerated at the center 4,[6][7] .…”

Section: Introductionmentioning

confidence: 99%

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A rare case of giant verruciform xanthoma in the palate

Rosa

Amorim

2014

RGO, Rev. Gaúch. Odontol.

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RESUMOO xantoma verruciforme é uma lesão rara de etiologia não determinada, que acomete, principalmente, a mucosa oral. Na maioria das vezes é assintomática, caracterizando-se por uma elevação bem-delimitada, de superfície rugosa ou papilar, e sua principal localização na boca é a gengiva. Com relação ao tamanho, a maioria das lesões não ultrapassa 2 cm no seu maior diâmetro. O objetivo do presente trabalho é relatar um caso raro de extenso xantoma verruciforme em paciente do gênero masculino, de 55 anos, apresentando lesão localizada no palato duro e na gengiva palatina. Clinicamente, a lesão possuía bordas bem-destacadas, de superfície levemente granular e coloração avermelhada, com consistência elástica, medindo aproximadamente 2,8 X 1,5cm. O exame histopatológico demonstrou a presença de proliferação do epitélio de revestimento, exibindo papilomatose, paraceratose e alongamento das cristas epiteliais. Na lâmina própria, células xantomatosas com citoplasma claro e vacuolado puderam ser observadas. O paciente encontra-se livre de recidivas após 18 meses de acompanhamento clínico. De acordo com extensa pesquisa em bases de dados (pubmed, medline, lilacs), o presente caso representa uma das maiores lesões do tipo xantoma verruciforme já relatadas na literatura.Termos de indexação: Mucosa bucal. Palato. Patologia bucal. Xantomatose.

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“…According to the etiology, given the occurrence of VX in masticatory mucosa, mainly in the gingiva, the possibility of trauma or inflammatory etiology can be con- minated VX was described involving multifocal lesions on the skin and in oral and genital mucosa (11). Clinically, differential diagnosis should include papilloma and verruga vulgar.…”

Section: Discussionmentioning

confidence: 99%

Verruciform xanthoma located in anterior gingiva

Hatakeyama¹,

Guilhermino²,

Brandão³

et al. 2010

J Clin Exp Dent

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Verruciform xanthoma (VX) is a relatively rare benign lesion and oral predominantly, which occasionally affects skin and genital mucosa. It appears as a papule or single plaque showing a verrucous or papillomatous aspect, with variable color from reddish pink to gray. In majority of oral cases, it affects gingiva and alveolar mucosa such a solitary lesion. Histopathological findings are foamy histiocytes within elongated dermal papillae. Treatment consists of conservative excision surgery and recurrence is rare. A clinical case is reported, located in anterior gingiva, showing good prognosis, without recurrence. There was no concomitant oral lesion associated. Local trauma was the only possibility suggested to be related to etiology. No relevant alterations in laboratory exams (hemogram, total cholesterol, HDL, LDL, VLDL, glycose and glycolized hemoglobin) were found. The origin of the lesion remains unclear and investigation for possible associations with other lesions that could present greater risk of carcinogenesis is required.

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Disseminated verruciform xanthoma

Cited by 23 publications

References 10 publications

Oral Verruciform Xanthoma Associated with Chronic Graft-Versus- Host Disease: A Report of Five Cases and a Review of the Literature

Oral Verruciform Xanthoma Associated with Chronic Graft-Versus- Host Disease: A Report of Five Cases and a Review of the Literature

A rare case of giant verruciform xanthoma in the palate

Verruciform xanthoma located in anterior gingiva

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