Disseminated lobomycosis

Abstract

Lobomycosis, also known as Jorge Lobo's disease, is a granulomatous, chronic fungal disease that involves the skin and subcutaneous tissue. The disease has been reported in South American, Central and North American countries, being particularly frequent in the Brazilian Amazon region. We report a case of disseminated lobomycosis in an 86 year-old Brazilian woman with a 55-year history of disseminated cutaneous lesions.

Lobomycosis: an emerging disease in humans and delphinidae

“…1b and 1c). 48–52 The lesions may be single or multiple. They have a tendency to become confluent over extensive areas of the body surface 51,52 .…”

Keloidal and verrucous lesions in an Amerindian patient

“…Although soil and vegetation are believed to be the chief habitat of the fungus, it has been increasingly identified in marine mammals 3 . In support of this, infection in humans has also been associated with proximity to water, raising the hypothesis that L. loboi may be a hydrophilic microorganism that penetrates the skin by trauma 1,3,4 …”

“…Although a specific pattern may dominate any given case, lesions are rarely monomorphous 3,4 . Silva and De Brito proposed a classification based on the morphological appearance of the lesions into five subtypes: infiltrated, keloidal, gummatous, ulcerative and verrucoid 5 .…”

Skin Infections

“…643,644 Admixed lymphocytes, plasma cells, and, less frequently, neutrophils can be present in smaller numbers. [646][647][648] Individual cells, which measure 6 to 12 µm, are interconnected by thin tube-like structures to form the chain-like arrangement (see Fig. 645 These lesions evolve with keloidal scarring, seen as brightly eosinophilic collagen bundles.…”