Disseminated infection with Trichosporon beigelii. Report of a case and review of the cutaneous and histologic manifestations

Dermatological manifestations of fungal infection in patients with febrile neutropaenia: A review of the literature

“…We discovered 54 publications with a total of 215 reported cases of cutaneous manifestations of fungal injury in patients with FNP (Table ). Descriptions of all lesions were either cited as described by the presenters of the case, or if such descriptions were lacking, described by the authors herein.…”

“…Disseminated infections caused by Trichosporon are also common in the FNP patient . In patients with haematologic malignancies, Trichosporon is the second most common disseminated yeast infection after Candida , with over 200 cases reported in the literature .…”

“…Disseminated trichosporonosis has a very poor prognosis, with a mortality rate of 42%‐87.5% . Similar to Candida , cutaneous lesions present as erythematous or purpuric papules and nodules sometimes with central necrosis or ulceration, localised on the trunk, face or limbs . Subcutaneous abscesses or haemorrhagic ulcerative nodules have also been reported …”

Identification of three yeast species using the conventional and internal transcribed spacer region sequencing methods as first or second global record from human superficial infections

“…They have been involved in a variety of opportunistic infections and have been recognised as emerging fungal pathogens in immunocompromised hosts . Studies also indicated that T. asahii , T. asteroids , T. cutaneum , T. faecale , T. inkin , T. mucoides or T. ovoides are involved in hypersensitivity pneumonitis, pulmonary infections and superficial infections, sinusitis, fungaemia, in HIV patients, a bone marrow transplant recipient, a solid organ transplant recipient and in a patient with severe aplastic anaemia . Members of the genus Trichosporon have occasionally been implicated as nail pathogens and in subcutaneous infections .…”

Fatal disseminated Trichosporon asahii fungemia in a child with acute lymphoblastic leukemia and a morbilliform eruption

“…Cutaneous involvement occurs in 30% of patients, most commonly presenting as purpuric papules and nodules with central necrosis or ulceration on the trunk, extremities, and face. 4,5 Other reported findings include a maculopapular eruption, necrotizing ulcers, and hemorrhagic bullae. 3,4 Histopathology may reveal dermal invasion by fungal elements and thromboembolic vasculitis.…”