Disseminated Granuloma Annulare

Psoriasis treatment with betamethasone dipropionate using short-term application and short-term occlusion

“…Niacinamide had to be taken for eight months before one patient cleared but the lesions returned when the drug was stopped (9). Claims for improvements with bismuth (JO) or antimalarials (11) have not been confirmed (10). Gold injections (12) and antihistamines (10) have not influenced the course of the disease and X-ray therapy has had no effect or produced only temporary improvement (13).…”

A Really Generalized Granuloma Annulare

“…According to them, 23 cases were known up to 1956. They presented a 49-year-old man with 300-500 papulous elements distributed more or less regularly over the body, except for the trunk and the head.Miller [10] showed a 61-ycar-old woman with an eruption of granu loma annulare on the inner aspects of the thighs, which gradually progressed and involved the upper extremities.A 26-year-old w hite man, recorded by Mandell [7] as a disseminated granuloma annulare, had a " generalized" symmetrical eruption which involved the buttocks, shoulders, lateral aspects of the lower extrem i ties, the abdomen, and the volar aspects of the forearms.In 1959, Frenken [4] described a generalized eruption of thousands of papules in a 54-year-old woman. Only the head, the feet and the palms of the hands wrere free.…”

“…A patient with plaque formation was presented by M ay and Couperus [8]. Mandel [7] dem onstrated a patient with hyperpigm ented oval and discrete skin coloured papules. Moyer's [11] patient was covered with thousands of 0.5-3 in in papules.…”