Disseminated Blue Nevus: Abnormal Nevoblast Migration or Proliferation?

Disseminated blue naevus and malignant blue naevus associated with excessive aromatase syndrome

“…Contrasting with our patient, the other three cases 4–6 showed no evidence of malignant transformation and no gynaecomastia or oestrogen excess. Oestrogens may have a role in promoting melanoma cell growth 7 .…”

“…There is only one previous report of disseminated blue naevus 4 . Two patients with congenital melanocytic naevus with widespread papules and variably sized nodules and tumours involving the entire body were described 5,6 .…”

Multiple congenital melanocytic naevi presenting with neurofibroma-like lesions complicated by malignant melanoma

“…Multiple congenital melanocytic naevi associated with neurofibroma‐like lesions have been reported previously 2–7 . Those cases were similar to our patient as giant CMN were present on the trunk and soft cutaneous nodules were arising from the skin involved by the naevi.…”

“…Multiple congenital melanocytic naevi associated with neurofibroma-like lesions have been reported previously. [2][3][4][5][6][7] Those cases were similar to our patient as giant CMN were present on the trunk and soft cutaneous nodules were arising from the skin involved by the naevi. The nodular component of the CMN started to develop in all these cases in adolescence or in early adulthood except for one case of a 6-year-old boy.…”

Pigmented plexiform neurofibroma: Distinction from a large congenital melanocytic nevus

“…5,6 Nonetheless, cases of large CMN with satellitosis that closely resembled and/or were initially misdiagnosed as NF1 have continued to be reported. [7][8][9][10][11][12][13][14][15] The converse is also true, as the large plexiform and diffuse neurofibromas seen in the setting of NF1 can mimic giant CMN. 16,17 In a recent study, 7 of 614 patients with NF1 (1%) had hypertrichotic pigmented lesions measuring greater than 3 cm in diameter.…”