Disseminate Lupus Erythematosus

Montgomery, Hamilton

doi:10.1001/archderm.1949.01530030052006

Cited by 91 publications

(11 citation statements)

References 4 publications

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“…The marked variability of the results can be seen when our data are compared with those from previous reports of patients with generalized DLE. Montgomery & McCreight (1949) described a total of 103 patients seen at the Mayo Clinic: 80 patients were seen before 1938 and 23 were seen during the next 9 years. Data from the 80 patients resembled our data with regard to female preponderance, absence of central-nervous-system abnormalities, and incidences of fever.…”

Section: Discussionmentioning

confidence: 99%

A Study of lupus erythematosus with particular reference to generalized discoid lupus

1978

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SUMMARY The classification of lupus erythematosus (LE) is difficult because of variable and multisystem involvement, occurrence of transitional forms, and overlapping with connective tissue disorders. One of the earliest attempts at classification was made by O'Leary (1934), who classified LE clinically into four main types: (1) chronic discoid lupus erythematosus (DLE), or fixed type with the typical erythematous, scaly, well‐demarcated eruption, usually showing follicular plugging and atrophy, confined to the head region; (2) generalized DLE, or chronic disseminated type differing from the localized discoid type in that the erythematous plaques are found not only on the head area but also below the neck region (O'Leary considered that constitutional systems were generally lacking in these two types); (3) subacute disseminated LE; and (4) acute disseminated LE. The last two categories reflect what we now call systemic lupus erythematosus (SLE) of varying severity. Many authors have used O'Leary's clinical classification, but progress in laboratory medicine—in particular the discovery of the LE cell—has led to other schemes, the most widely accepted at present being that related to the American Rheumatism Association's (ARA) preliminary criteria for the diagnosis of SLE (Cohen et al., 1971). These criteria have been criticized by many authorities because they do not include important data, such as those relative to the antinuclear antibody test, serum anti‐native‐DNA, serum complement levels, many neurological abnormalities, renal biopsy changes, and cutaneous immunofluorescent (IF) findings. However, Dubois (1974b) pointed out that all categorizations of LE are arbitrary, and he accepted the ARA criteria as a successful method for differentiating LE. This report involves the clinical and laboratory findings in 123 patients with LE seen at the Mayo Clinic during the 3‐year period 1971–1974 and an assessment of the validity and usefulness of O'Leary's classification.

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Section: Discussionmentioning

confidence: 99%

A Study of lupus erythematosus with particular reference to generalized discoid lupus

1978

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“…It would not appear to be unduly sensitive, however, since the incidence of biological false positive reactions in our study using the RPR test was 15 per cent., which is comparable to the previously reported incidence of 10-20 per cent. in most series (Montgomery and McCreight, 1949;Zellmann, 1952). Summary A comparison of the RPR and VDRL tests was undertaken in order to determine whether the RPR card test might miss some biological false positive reactions for syphilis in cases of systemic lupus erythematosus, as it does in leprosy.…”

Section: Discussionmentioning

confidence: 98%

Comparison of rapid plasma reagin card test and venereal disease research laboratory test in the detection of biological false positive reactions in systemic lupus erythematosus.

Dorwart¹,

Myers²

1974

Sexually Transmitted Infections

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“…There was no mention of a single case in which the systemic form developed into the chronic discoid type. Nor was such a change described by Montgomery [12], or by Montgomery and McCreight [13], respectively reporting 154 and 132 cases of systemic lupus erythem a tosus.…”

Section: Discussionmentioning

confidence: 99%