Disruption of Sensorimotor Cortical Oscillations by Visual Interference Predicts the Altered Motor Performance of Persons with Cerebral Palsy

Busboom, Morgan T.; Hoffman, Rashelle M.; Spooner, Rachel K.; Taylor, Brittany K.; Baker, Sarah E.; Trevarrow, Michael P.; Wilson, Tony W.; Kurz, Max J.

doi:10.1016/j.neuroscience.2023.11.017

Cited by 1 publication

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“…Several investigations have shown that the beta ERD, gamma ERS and PMBR tend to be weaker when individuals with CP plan and execute their hand motor actions 24 – 26 . Furthermore, the extent of the deviations seen in the beta and gamma sensorimotor cortical oscillations appear to be connected with slower reaction times, deviations in muscular performance, and the extent of motor execution errors in those with CP 12 , 24 – 28 .…”

Section: Introductionmentioning

confidence: 99%

Adults with cerebral palsy exhibit uncharacteristic cortical oscillations during an adaptive sensorimotor control task

Hinton,

Busboom,

Embury

et al. 2024

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Prior research has shown that the sensorimotor cortical oscillations are uncharacteristic in persons with cerebral palsy (CP); however, it is unknown if these altered cortical oscillations have an impact on adaptive sensorimotor control. This investigation evaluated the cortical dynamics when the motor action needs to be changed “on-the-fly”. Adults with CP and neurotypical controls completed a sensorimotor task that required either proactive or reactive control while undergoing magnetoencephalography (MEG). When compared with the controls, the adults with CP had a weaker beta (18–24 Hz) event-related desynchronization (ERD), post-movement beta rebound (PMBR, 16–20 Hz) and theta (4–6 Hz) event-related synchronization (ERS) in the sensorimotor cortices. In agreement with normative work, the controls exhibited differences in the strength of the sensorimotor gamma (66–84 Hz) ERS during proactive compared to reactive trials, but similar condition-wise changes were not seen in adults with CP. Lastly, the adults with CP who had a stronger theta ERS tended to have better hand dexterity, as indicated by the Box and Blocks Test and Purdue Pegboard Test. These results may suggest that alterations in the theta and gamma cortical oscillations play a role in the altered hand dexterity and uncharacteristic adaptive sensorimotor control noted in adults with CP.

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