Dislocation of Dexamethasone Intravitreous Implant

Corneal graft failure due to migration of Ozurdex™ implant into the anterior chamber

“…There have been 29 cases in the literature of Ozurdex™ implant migration into the AC and corneal oedema developed in 24 (83%) of these cases. 5 , 6 , 7 , 8 , 9 , 10 , 11 , 12 , 13 , 14 , 15 , 16 Three risk factors noted for implant migration are a defective or absent posterior lens capsule, history of a prior vitrectomy and presence of a peripheral iridectomy (PI). However, the presence of any of these risk factors does not necessarily mean that migration will occur.…”

“… 2 There have been reports in the literature of migration of the implant into the anterior chamber (AC) that resulted in corneal decompensation. 5 , 6 , 7 , 8 , 9 , 10 , 11 , 12 , 13 We describe corneal endothelial graft failure secondary to Ozurdex™ implant migration into the anterior chamber, and the subsequent management and outcome.…”

Corneal graft failure due to migration of Ozurdex™ implant into the anterior chamber

“…There have been 29 cases in the literature of Ozurdex™ implant migration into the AC and corneal oedema developed in 24 (83%) of these cases. 5 , 6 , 7 , 8 , 9 , 10 , 11 , 12 , 13 , 14 , 15 , 16 Three risk factors noted for implant migration are a defective or absent posterior lens capsule, history of a prior vitrectomy and presence of a peripheral iridectomy (PI). However, the presence of any of these risk factors does not necessarily mean that migration will occur.…”

“… 2 There have been reports in the literature of migration of the implant into the anterior chamber (AC) that resulted in corneal decompensation. 5 , 6 , 7 , 8 , 9 , 10 , 11 , 12 , 13 We describe corneal endothelial graft failure secondary to Ozurdex™ implant migration into the anterior chamber, and the subsequent management and outcome.…”

Management of anterior chamber dislocation of a dexamethasone intravitreal implant: a case report

“…Despite this evidence, the choice of the technique adopted should depend on the location and positioning of the dexamethasone implant relative to other intraocular structures. Thus, surgical procedures are sometimes inevitable to relocate the implant and to manage corneal decompensation and elevated intraocular pressure [ 19 , 20 ].…”

First-line treatment algorithm and guidelines in center-involving diabetic macular edema

“…DEX-I migration into the anterior chamber has been reported in the literature. 67–81 In all cases, this complication occurred in a pseudophakic or aphakic eye and mostly in cases with an open or defective lens capsule. Anterior chamber intraocular lens (IOL), iris-fixated IOL, scleral-fixated posterior chamber IOL, and sulcus IOL are therefore the main risk factors for anterior DEX-I migration.…”

Corneal graft failure due to migration of Ozurdex™ implant into the anterior chamber

“…There have been 29 cases in the literature of Ozurdex™ implant migration into the AC and corneal oedema developed in 24 (83%) of these cases. 5 , 6 , 7 , 8 , 9 , 10 , 11 , 12 , 13 , 14 , 15 , 16 Three risk factors noted for implant migration are a defective or absent posterior lens capsule, history of a prior vitrectomy and presence of a peripheral iridectomy (PI). However, the presence of any of these risk factors does not necessarily mean that migration will occur.…”

“… 2 There have been reports in the literature of migration of the implant into the anterior chamber (AC) that resulted in corneal decompensation. 5 , 6 , 7 , 8 , 9 , 10 , 11 , 12 , 13 We describe corneal endothelial graft failure secondary to Ozurdex™ implant migration into the anterior chamber, and the subsequent management and outcome.…”

Management of anterior chamber dislocation of a dexamethasone intravitreal implant: a case report

“…Despite this evidence, the choice of the technique adopted should depend on the location and positioning of the dexamethasone implant relative to other intraocular structures. Thus, surgical procedures are sometimes inevitable to relocate the implant and to manage corneal decompensation and elevated intraocular pressure [ 19 , 20 ].…”

First-line treatment algorithm and guidelines in center-involving diabetic macular edema

“…DEX-I migration into the anterior chamber has been reported in the literature. 67–81 In all cases, this complication occurred in a pseudophakic or aphakic eye and mostly in cases with an open or defective lens capsule. Anterior chamber intraocular lens (IOL), iris-fixated IOL, scleral-fixated posterior chamber IOL, and sulcus IOL are therefore the main risk factors for anterior DEX-I migration.…”

Corneal graft failure due to migration of Ozurdex™ implant into the anterior chamber

“…There have been 29 cases in the literature of Ozurdex™ implant migration into the AC and corneal oedema developed in 24 (83%) of these cases. 5 , 6 , 7 , 8 , 9 , 10 , 11 , 12 , 13 , 14 , 15 , 16 Three risk factors noted for implant migration are a defective or absent posterior lens capsule, history of a prior vitrectomy and presence of a peripheral iridectomy (PI). However, the presence of any of these risk factors does not necessarily mean that migration will occur.…”

“… 2 There have been reports in the literature of migration of the implant into the anterior chamber (AC) that resulted in corneal decompensation. 5 , 6 , 7 , 8 , 9 , 10 , 11 , 12 , 13 We describe corneal endothelial graft failure secondary to Ozurdex™ implant migration into the anterior chamber, and the subsequent management and outcome.…”

Management of anterior chamber dislocation of a dexamethasone intravitreal implant: a case report

“…Despite this evidence, the choice of the technique adopted should depend on the location and positioning of the dexamethasone implant relative to other intraocular structures. Thus, surgical procedures are sometimes inevitable to relocate the implant and to manage corneal decompensation and elevated intraocular pressure [ 19 , 20 ].…”

First-line treatment algorithm and guidelines in center-involving diabetic macular edema

“…DEX-I migration into the anterior chamber has been reported in the literature. 67–81 In all cases, this complication occurred in a pseudophakic or aphakic eye and mostly in cases with an open or defective lens capsule. Anterior chamber intraocular lens (IOL), iris-fixated IOL, scleral-fixated posterior chamber IOL, and sulcus IOL are therefore the main risk factors for anterior DEX-I migration.…”