“…Further, we found that this association was independent of the presence of a normal ejection fraction and traditional cardiovascular risk factors like hypertension and smoking. In a letter to the editor, Giollo et al 1 present data from a series of 235 patients with RA 3. In contrast to our findings, Giollo et al 1 did not find an association between RA disease activity and LV systolic myocardial function when assessed by scMWS or tissue Doppler mitral annular systolic velocity (S´), despite a much higher median RA disease activity in their population 3.…”