Journal of Chromatography A 2012 DOI: 10.1016/j.chroma.2012.02.003 View full text
J. Rodríguez, G. Castañeda, A.M. Contento, L. Muñoz

Abstract: A micellar electrokinetic chromatography (MEKC) method was developed for the determination of paclitaxel, morphine and codeine in human urine from patients under cancer treatment. The background electrolyte consisted of a borate buffer (pH 9.2; 20 mM) with sodium dodecyl sulfate (60 mM) and 5% MeOH. The applied voltage was 25 kV, temperature was 20 °C and the sample injection was performed in the hydrodynamic mode. All analyses were carried out in a fused silica capillary with an internal diameter of 75 μm and…

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