Dipyridamole inhibits intracellular calcium transients in isolated rat arteriole smooth muscle cells

Saino, Tomoyuki; Misaki, Toshinari; Matsuura, Makoto; Shikanai, Toshiki; Satoh, Yuichi

doi:10.1679/aohc.71.235

Cited by 4 publications

(1 citation statement)

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“…Dipyridamole works by inhibiting adenosine uptake into platelets and therefore reducing adenosine diphosphate (ADP)‐ and platelet activating factor (PAF)‐induced platelet aggregation . It is licensed for:…”

Section: Antiplatelet Agentsmentioning

confidence: 99%

Novel anticoagulants and antiplatelet agents; a guide for the urologist

Ellis

Camm

Datta

2015

BJU Int

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Novel oral anti‐coagulants (NOACs) are increasingly being used in clinical practice and are set to almost entirely replace the vitamin K antagonists, such as warfarin, in the near future. Similarly, new antiplatelet agents are now regularly used in place of older agents, such as aspirin and clopidogrel. In an ageing population, with an increasing burden of complex comorbidities, urologists will frequently encounter patients who will be using such agents. Some background knowledge, and an understanding, of these drugs and the issues that surround their usage, is essential. The present article will provide readers with an understanding of these new drugs, including their mechanisms of action, the up‐to‐date evidence justifying their recent introduction into clinical practice and the appropriate interval for stopping them before surgery. It will also consider the risks of perioperative bleeding for patients taking these drugs and the risks of venous thromboembolism in those in whom they are stopped. Strategies to manage anticoagulant‐associated bleeding are discussed.

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Section: Antiplatelet Agentsmentioning

confidence: 99%