Diosgenin derivatives developed from Pd(ii) catalysed dehydrogenative coupling exert an effect on breast cancer cells by abrogating their growth and facilitating apoptosis via regulating the AKT1 pathway

Abstract

Pd(ii) chromone Schiff base complex catalysed the dehydrogenative coupling of diosgenin and the obtained derivatives induced apoptosis by inhibiting AKT1 signaling pathway in breast cancer cells.