Digital Numbers Constructed by Fine Patterned Polydopamine on DNA Templates

Abstract

Using DNA nanostructures as templates to synthesize shape-controlled polydopamine (PDA) is a promising strategy to realize the fabrication of exquisite PDA nanomaterials. However, previous studies using small DNA tiles as templates could only afford very simple structures such as lines and crosses due to the limited space on the template and the relatively low resolution of the PDA nanopatterns. Therefore, the best resolution of the PDA nanostructures that can be achieved by this technique is carefully investigated. And by connecting several DNA tiles together, larger DNA templates are built up and achieve the synthesis of complicated digital nanopatterned PDA structures.

Recent Advances of DNA Origami Technology and Its Application in Nanomaterial Preparation

“…[77] Our team further constructed a larger DNA template by concatenating several DNA tiles together and achieved the synthesis of complex digital nanopatterned PDA structures on DNA origami (Figure 10D). [78] In addition to using G4/hemin to mimic horseradish peroxidase to fabricate PDA nanostructures, our team developed another method based on atom-transfer radical polymerization (ATRP) by functionalizing DNA ends to achieve controllable preparation of nanopatterned polymer materials on DNA tiles.…”

“…[ 77 ] Our team further constructed a larger DNA template by concatenating several DNA tiles together and achieved the synthesis of complex digital nanopatterned PDA structures on DNA origami (Figure 10D). [ 78 ]…”