Diffusion-weighted MR imaging of normal and abnormal scrotum: preliminary results

Tsili, Athina C.; Argyropoulou, Maria I.; Giannakis, Dimitrios; Tsampalas, Stavros; Sofikitis, Nikolaos; Tsampoulas, Konstantinos

doi:10.1038/aja.2011.172

Cited by 64 publications

(64 citation statements)

References 28 publications

(110 reference statements)

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“…Diffusion restriction may be observed as a result of inflammation, trauma, ischemia, tumor or fibrosis [7,9]. Investigating the ADC values is a promising radiological method in determining testicular fibrosis in patients with varicocele [3,10]. To our knowledge, there is only one study in the literature on the testis diffusion in patients with varicocele, and in that study, the testicular ADC values of patients with varicocele and healthy volunteers were found to be different [3].…”

Section: Introductionmentioning

confidence: 96%

Comparison of diffusion-weighed MRI findings of the testis in patients with the advanced stage unilateral testicular varicocele

Burulday¹,

Şahan²,

Erdem³

et al. 2017

Med-Science

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The aim of this study was to compare the testicular apparent diffusion coefficient (ADC) values of the patients with unilateral advanced stage varicocele and healthy volunteers. Twenty-seven patients with unilateral advanced stage varicocele and twenty-seven healthy volunteers were included in the study. Those with a diagnosis of clinical varicocele and the healthy volunteers were examined clinical and color Doppler ultrasonography. Patients with a unilateral (left) varicocele clinically grade III, color Doppler ultrasound grade IV-V were included in the study. All the patients and healthy volunteers were obtained ADC values. Mean values were calculated and statistical comparison was performed. ADC values were analysed by using an independent t test for each participant. Pearson's correlation test was used for the comparison of left pampiniform venous diameter and both testicular parenchymal ADC values. Left testicular ADC values were observed to be significantly lower when a comparison of the testicular parenchymal with left advanced stage varicocele and healthy volunteers revealed significantly low left testicular ADC values in patients (p<0.05) Furthermore, a negative correlation was detected between the increase in the left testicular venous diameter and parenchymal ADC values of the bilateral testis in patients with left advanced stage varicocele (left p= -624, right p= -0.382). Diffusion weighted magnetic resonance imaging may be beneficial in defining the testicular damage in patients with varicocele.

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Section: Introductionmentioning

confidence: 96%

Comparison of diffusion-weighed MRI findings of the testis in patients with the advanced stage unilateral testicular varicocele

Burulday¹,

Şahan²,

Erdem³

et al. 2017

Med-Science

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“…A few recently published reports have addressed the diagnostic performance of DWI in the evaluation of various scrotal pathologies such as detection and localization of impalpable testes, diagnosis of testicular torsion and differentiation between normal, benign and malignant scrotal contents (9,(18)(19)(20).…”

Section: Introductionmentioning

confidence: 99%

Magnetic resonance imaging for detection of non palpable undescended testes: Diagnostic accuracy of diffusion-weighted MRI in comparison with laparoscopic findings

Ali

Abdel-Gawad

Magdi

et al. 2015

The Egyptian Journal of Radiology and Nuclear Medicine

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Purpose: The purpose of this study is to assess the value of adding diffusion-weighted sequences (DW) to routine magnetic resonance imaging (MRI) in identifying and locating nonpalpable undescended testes. Materials and methods: This prospective study included 51 patients with age ranges from 2 to 15 years presenting with non-palpable undescended testes. MRI was done using1.5 MRI machine. MRI examination included axial and coronal spin-echo T1-weighted sequence, axial and coronal fat suppressed spin-echo T2-weighted sequence and axial DWI. Images were interpreted for the presence or absence and the location of the undescended testes. Testes were recognized by their elliptical shape and hyperintensity. Testes were classified into three anatomic regions: intracanalicular, low intra-abdominal, and high intra-abdominal. Laparoscopy was used as a gold standard. Results: Conventional MRI showed a sensitivity, specificity and accuracy of 87.23%, 50% and 83% respectively. DW MRI showed a sensitivity, specificity and accuracy of 91.5%, 66.7% and 88.6% respectively. The combined usage of conventional and DW MRI yielded a sensitivity, specificity and accuracy of 95.8%, 100% and 96.2%. Conclusion: DWI especially performed at a high b value improves detection of undescended testes.

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“…Magnetic Resonance (MR) of the testis, by means of classic T1 and T2 weighted sequences, is the second level choice to study the parenchymal pattern, the vascularization and for the morphovolumetric characterization [9][10][11][12][13][14].…”

Section: Introductionmentioning

confidence: 99%

Role of MR Spectroscopy (H1-MRS) of the Testis in Men with Semen Analysis Altered

Parenti¹,

Albarello²

2016

Reprod Syst Sex Disord

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Purpose: Proton magnetic resonance spectroscopy (1 H-MRS) has been proposed as a tool to assess male infertility providing metabolic signatures related to the spermatogenesis in the testis. This study sought to identify the role of 1 H-MRS in the diagnosis of infertility in patients with semen analysis altered. Materials and Methods:14 patients (27 testicles) with fertility problems and with an altered semen analysis (5 oligospermia, 3 asthenospermia, 6 oligoasthenospermia) and 9 controls (18 testicles) with normal spermatogenesis assessed (men with prior paternity and normal semen analysis) and normal testicles at magnetic resonance (MR) and ultrasonography (US) with colour Doppler (CD) examination were included. All patients underwent testis US and CD investigation, conventional MR examination at 1.5T including T1 and T2 weighted images in three orthogonal planes and proton magnetic resonance spectroscopy (1 H-MRS) with single-voxel PRESS (TR 2000 ms / TE 31 ms). Major metabolites peaks (choline, creatine, lipids, lactate) were calculated and compared between the patients and controls.Results: Mean choline peak in the semen analysis altered group was statistically significantly lower than the normal group (0.69 vs 1.34, 95% CI: 0.52 -0.85; p < 0.001). 18 testicles within semen analysis altered group (66,7%) had both MR and US examination negative but mean choline peak lower then controls (1.09 vs 1.34, p < 0.001). 7 testicles of those presented also varicocele at CD investigation. Conclusion:1 H-MRS revealed a significant shift towards lower choline peak in patients with semen analysis altered compared to controls with normal spermatogenesis. Moreover 1 HMRS provided to find out spermatogenesis disorder in patients with normal testis at MR and US examination.

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Diffusion-weighted MR imaging of normal and abnormal scrotum: preliminary results

Cited by 64 publications

References 28 publications

Comparison of diffusion-weighed MRI findings of the testis in patients with the advanced stage unilateral testicular varicocele

Comparison of diffusion-weighed MRI findings of the testis in patients with the advanced stage unilateral testicular varicocele

Magnetic resonance imaging for detection of non palpable undescended testes: Diagnostic accuracy of diffusion-weighted MRI in comparison with laparoscopic findings

Role of MR Spectroscopy (H1-MRS) of the Testis in Men with Semen Analysis Altered

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