Diffusion-Weighted Magnetic Resonance Imaging for Characterization of Focal Liver Masses

Ertürk, Şükrü Mehmet; Ichikawa, Tomoaki; Sano, Katsuhiro; Motosugi, Utarou; Sou, Hironobu; Araki, Tsutomu

doi:10.1097/rct.0b013e3181591cf2

Cited by 34 publications

(16 citation statements)

References 23 publications

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“…Furthermore, ADC cutoff of right hepatic lobe in our study was smaller compared to that of whole liver in previous studies (Ichikawa et al, 1998;Kim et al, 1999;Taouli et al, 2003;Bruegel et al, 2008;Erturk et al, 2008;Gourtsoyianni et al, 2008;Parikh et al, 2008;Vossen et al, 2008). In addition to the above reasons, the variability can be partially attributed to the difference of research objects.…”

Section: Discussioncontrasting

confidence: 55%

Diffusion-Weighted Imaging for the Left Hepatic Lobe has Higher Diagnostic Accuracy for Malignant Focal Liver Lesions

Han

Yin²,

Xiu³

et al. 2014

Asian Pacific Journal of Cancer Prevention

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Background: This study was conducted to investigate whether apparent diffusion coefficient (ADC) measurements by dividing the liver into left and right hepatic lobes may be utilized to improve the accuracy of differential diagnosis of benign and malignant focal liver lesions. Materials and Methods: A total of 269 consecutive patients with 429 focal liver lesions were examined by 3-T magnetic resonance imaging that included diffusion-weighted imaging. For 58 patients with focal liver lesions of the same etiology in left and right hepatic lobes, ADCs of normal liver parenchyma and focal liver lesions were calculated and compared using the paired t-test. For all 269 patients, ADC cutoffs for focal liver lesions and diagnostic accuracy in the left hepatic lobe, right hepatic lobe and whole liver were evaluated by receiver operating characteristic curve analysis. Results: For the group of 58 patients, mean ADCs of normal liver parenchyma and focal liver lesions in the left hepatic lobe were significantly higher than those in the right hepatic lobe. For differentiating malignant lesions from benign lesions in all patients, the sensitivity and specificity were 92.6% and 92.0% in the left hepatic lobe, 94.4% and 94.4% in the right hepatic lobe, and 90.4% and 94.7% in the whole liver, respectively. The area under the curve of the right hepatic lobe, but not the left hepatic lobe, was higher than that of the whole liver. Conclusions: ADCs of normal liver parenchyma and focal liver lesions in the left hepatic lobe were significantly higher than those in the right hepatic lobe. Optimal ADC cutoff for focal liver lesions in the right hepatic lobe, but not in the left hepatic lobe, had higher diagnostic accuracy compared with that in the whole liver.Keywords: Diffusion-weighted imaging -apparent diffusion coefficient -focal liver lesion -left and right hepatic lobes

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Section: Discussioncontrasting

confidence: 55%

Diffusion-Weighted Imaging for the Left Hepatic Lobe has Higher Diagnostic Accuracy for Malignant Focal Liver Lesions

Han

Yin²,

Xiu³

et al. 2014

Asian Pacific Journal of Cancer Prevention

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“…These poor results might be explained by the diagnostic criterion chosen for diagnosing liver metastasis on contrast-enhanced images, which was hypervascularization. Indeed, this suggestive pattern is found in only 70% of the liver metastases (10,20,21). We hypothesize that the high signal-tonoise ratio of our DW sequence owing to a high number of excitations and the high cellularity of NET could explain our results (20).…”

Section: Gastrointestinal Imaging: Detection Of Liver Metastases Frommentioning

confidence: 72%

High Sensitivity of Diffusion-weighted MR Imaging for the Detection of Liver Metastases from Neuroendocrine Tumors: Comparison with T2-weighted and Dynamic Gadolinium-enhanced MR Imaging

d’Assignies¹,

Fina²,

Bruno³

et al. 2013

Radiology

170

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“…8,39 -42 Diffusion-weighted MR imaging using high-b-value achieved detection of colorectal, pancreatic adenocarcinoma and focal liver masses with high sensitivity and specificity. 39,40,42 Combined reading of diffusion-weighted images and unenhanced T1/T2-weighted images (ie, the basic image set) had higher accuracy for the detection of hepatic metastases than SPIO-enhanced MR images. 8 In the present study, SPIO-enhanced MR sets using PROPELLER technique enabled improved detection of hepatic lesions 1 cm in diameter or smaller as well as lesions larger than 1 cm than the MR sets using diffusionweighted images.…”

Section: Discussionmentioning

confidence: 99%

Improved Detection of Hepatic Metastases From Pancreatic Cancer Using Periodically Rotated Overlapping Parallel Lines With Enhanced Reconstruction (PROPELLER) Technique After SPIO Administration

Hirokawa¹,

Isoda²,

Okada³

et al. 2010

Investigative Radiology

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Diffusion-Weighted Magnetic Resonance Imaging for Characterization of Focal Liver Masses

Abstract: Diffusion-weighted imaging with a b value of 1000 s/mm2 and SENSE has the potential to differentiate hepatic focal lesions with improved sensitivity and specificity.

Cited by 34 publications

References 23 publications

Diffusion-Weighted Imaging for the Left Hepatic Lobe has Higher Diagnostic Accuracy for Malignant Focal Liver Lesions

Diffusion-Weighted Imaging for the Left Hepatic Lobe has Higher Diagnostic Accuracy for Malignant Focal Liver Lesions

High Sensitivity of Diffusion-weighted MR Imaging for the Detection of Liver Metastases from Neuroendocrine Tumors: Comparison with T2-weighted and Dynamic Gadolinium-enhanced MR Imaging

Improved Detection of Hepatic Metastases From Pancreatic Cancer Using Periodically Rotated Overlapping Parallel Lines With Enhanced Reconstruction (PROPELLER) Technique After SPIO Administration

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